Abstract
Cardiac arrest (CA) is a clinical condition defined by the absence of an effective circulatory blood flow due to the inability of the heart to provide consistent hemodynamic support.
Two main characteristics challenge the treatment of CA: its unpredictable onset and the very short time in which to intervene in order to avoid irreversible and dramatic organ damage.
The cardiology community has attempted to address the difficulties related to the management of CA through the development of standardized protocols aimed at treating CA. The current guidelines place strong consideration on the initial rhythm and the restoration of spontaneous circulation with resuscitation. What is not sufficiently emphasized in the current approach to CA is the dynamic transition of different cardiac rhythms during the acute event. In this chapter, the temporal sequence of different cardiac arrhythmias during CA and their prognostic significance are described. The proarrhythmic effects of pharmacological and electrical treatment utilized during the resuscitation are also discussed. In recent years, therapeutic hypothermia has been introduced for the treatment of survivors of CA in an effort to reduce neurological damage. Electrocardiographic abnormalities associated with therapeutic hypothermia are briefly described.
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References
The European resuscitation Council Guidelines for resuscitation. 2010. Available from: http://resuscitation-guidlines.articlesmotion.com/resource-center.
Nichol G, Stiell IG, Laupacis A, Pham B, De Maio VJ, Wells GA. A cumulative meta-analysis of the effectiveness of defibrillator-capable emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med. 1999;34(4 Pt 1):517–25.
Grasner JT, Meybohm P, Fischer M, Bein B, Wnent J, Franz R, et al. A national resuscitation registry of out-of-hospital cardiac arrest in Germany-a pilot study. Resuscitation. 2009;80(2):199–203.
Grmec S, Krizmaric M, Mally S, Kozelj A, Spindler M, Lesnik B. Utstein style analysis of out-of-hospital cardiac arrest–bystander CPR and end expired carbon dioxide. Resuscitation. 2007;72(3):404–14.
Chugh SS, Reinier K, Teodorescu C, Evanado A, Kehr E, Al Samara M, et al. Epidemiology of sudden cardiac death: clinical and research implications. Prog Cardiovasc Dis. 2008;51(3):213–28.
Cummins RO, Chamberlain D, Hazinski MF, Nadkarni V, Kloeck W, Kramer E, et al. Recommended guidelines for reviewing, reporting, and conducting research on in-hospital resuscitation: the in-hospital ‘Utstein style’. American Heart Association. Circulation. 1997;95(8):2213–39.
Eisenberg MS, Cummins RO, Damon S, Larsen MP, Hearne TR. Survival rates from out-of-hospital cardiac arrest: recommendations for uniform definitions and data to report. Ann Emerg Med. 1990;19(11):1249–59.
Martens PR, Russell JK, Wolcke B, Paschen H, Kuisma M, Gliner BE, et al. Optimal Response to Cardiac Arrest study: defibrillation waveform effects. Resuscitation. 2001;49(3):233–43.
White RD, Russell JK. Refibrillation, resuscitation and survival in out-of-hospital sudden cardiac arrest victims treated with biphasic automated external defibrillators. Resuscitation. 2002;55(1):17–23.
van Alem AP, Post J, Koster RW. VF recurrence: characteristics and patient outcome in out-of-hospital cardiac arrest. Resuscitation. 2003;59(2):181–8.
Skogvoll E, Eftestol T, Gundersen K, Kvaloy JT, Kramer-Johansen J, Olasveengen TM, et al. Dynamics and state transitions during resuscitation in out-of-hospital cardiac arrest. Resuscitation. 2008;78(1):30–7.
Meaney PA, Nadkarni VM, Kern KB, Indik JH, Halperin HR, Berg RA. Rhythms and outcomes of adult in-hospital cardiac arrest. Crit Care Med. 2010;38(1):101–8.
Hallstrom A, Rea TD, Mosesso Jr VN, Cobb LA, Anton AR, Van Ottingham L, et al. The relationship between shocks and survival in out-of-hospital cardiac arrest patients initially found in PEA or asystole. Resuscitation. 2007;74(3):418–26.
Salcido DD, Stephenson AM, Condle JP, Callaway CW, Menegazzi JJ. Incidence of rearrest after return of spontaneous circulation in out-of-hospital cardiac arrest. Prehosp Emerg Care. 2010;14(4):413–8.
Neset A, Nordseth T, Kramer-Johansen J, Wik L, Olasveengen TM. Effects of adrenaline on rhythm transitions in out-of-hospital cardiac arrest. Acta Anaesthesiol Scand. 2013;57(10):1260–7.
Bourque D, Daoust R, Huard V, Charneux M. beta-Blockers for the treatment of cardiac arrest from ventricular fibrillation? Resuscitation. 2007;75(3):434–44.
Pires LA, Hull ML, Nino CL, May LM, Ganji JR. Sudden death in recipients of transvenous implantable cardioverter defibrillator systems: terminal events, predictors, and potential mechanisms. J Cardiovasc Electrophysiol. 1999;10(8):1049–56.
Luceri RM, Habal SM, Castellanos A, Thurer RJ, Waters RS, Brownstein SL. Mechanism of death in patients with the automatic implantable cardioverter defibrillator. Pacing Clin Electrophysiol. 1988;11(11 Pt 2):2015–22.
Kelly PA, Cannom DS, Garan H, Mirabal GS, Harthorne JW, Hurvitz RJ, et al. The automatic implantable cardioverter-defibrillator: efficacy, complications and survival in patients with malignant ventricular arrhythmias. J Am Coll Cardiol. 1988;11(6):1278–86.
Mercando AD, Furman S, Johnston D, Frame R, Brodman R, Kim SG, et al. Survival of patients with the automatic implantable cardioverter defibrillator. Pacing Clin Electrophysiol. 1988;11(11 Pt 2):2059–63.
Mitchell LB. Use of the implantable cardioverter-defibrillator in patients with coronary artery spasm as the apparent cause of spontaneous life-threatening ventricular tachycardia or ventricular fibrillation: crossing the spasm sudden death chasm. J Am Coll Cardiol. 2012;60(10):914–6.
Van Vleet JF, Tacker Jr WA, Geddes LA, Ferrans VJ. Acute cardiac damage in dogs given multiple transthoracic shocks with a trapezoidal wave-form defibrillator. Am J Vet Res. 1977;38(5):617–26.
Tedeschi CG, White Jr CW. A morphologic study of canine hearts subjected to fibrillation, electrical defibrillation and manual compression. Circulation. 1954;9(6):916–21.
Tsuji Y. Electrical storm and calcium signaling: a review. J Electrocardiol. 2011;44(6):725–9.
Tsuji Y, Hojo M, Voigt N, El-Armouche A, Inden Y, Murohara T, et al. Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm. Circulation. 2011;123(20):2192–203.
Lesigne C, Levy B, Saumont R, Birkui P, Bardou A, Rubin B. An energy-time analysis of ventricular fibrillation and defibrillation thresholds with internal electrodes. Med Biol Eng. 1976;14(6):617–22.
Chen PS, Shibata N, Dixon EG, Martin RO, Ideker RE. Comparison of the defibrillation threshold and the upper limit of ventricular vulnerability. Circulation. 1986;73(5):1022–8.
Oku K, Kuboyama K, Safar P, Obrist W, Sterz F, Leonov Y, et al. Cerebral and systemic arteriovenous oxygen monitoring after cardiac arrest. Inadequate cerebral oxygen delivery. Resuscitation. 1994;27(2):141–52.
Hypothermia after Cardiac Arrest Study G. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002;346(8):549–56.
Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002;346(8):557–63.
Lebiedz P, Meiners J, Samol A, Wasmer K, Reinecke H, Waltenberger J, et al. Electrocardiographic changes during therapeutic hypothermia. Resuscitation. 2012;83(5):602–6.
Riaz A, Hieb H, Foley B, Mulvihill N, Crean P, Murphy RT, et al. Safety of therapeutic hypothermia in post VF/VT cardiac arrest patients. Ir Med J. 2013;106(2):55–6.
Piktel JS, Jeyaraj D, Said TH, Rosenbaum DS, Wilson LD. Enhanced dispersion of repolarization explains increased arrhythmogenesis in severe versus therapeutic hypothermia. Circ Arrhythm Electrophysiol. 2011;4(1):79–86.
Huang CH, Tsai MS, Hsu CY, Chen WJ. Images in cardiovascular medicine. Therapeutic hypothermia-related torsade de pointes. Circulation. 2006;114(14):e521–2.
Wu ET, Huang SC, Chi NH, Lin MT, Ko WJ, Wang SS, et al. Idioventricular rhythm induced by therapeutic hypothermia. Resuscitation. 2008;76(3):471–3.
Richter S, Ehrlich JR, Fassbender S, Fichtlscherer S. Malignant Osborn waves during therapeutic hypothermia. Europace. 2009;11(5):668–9.
Khan JN, Prasad N, Glancy JM. QTc prolongation during therapeutic hypothermia: are we giving it the attention it deserves? Europace. 2010;12(2):266–70.
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Proietti, R., Joza, J., Costea, F., Toma, M., Mǎnǎstireanu, D., Essebag, V. (2014). Cardiac Arrest Arrhythmias. In: Kibos, A., Knight, B., Essebag, V., Fishberger, S., Slevin, M., Țintoiu, I. (eds) Cardiac Arrhythmias. Springer, London. https://doi.org/10.1007/978-1-4471-5316-0_21
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