Abstract
Synthesis of a molecularly imprinted polymer (MIP) by two-step swelling and polymerization is described. Monodisperse, spherical MIP particles, whose diameters are ca. 5–9μm, are prepared using a polystyrene particle as a shape template and dibutyl phthalate as an activating solvent. The obtained MIPs are suitable for separation media in liquid chromatography or solid-phase extraction media. Procedures for synthesis of MIPs and restricted access media (RAM)-MIP, packing of MIPs and RAM-MIPs, and application of MIPs and RAM-MIPs for selective separation and extraction of a target compound(s) are described.
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Haginaka, J. (2021). Synthesis of Molecularly Imprinted Polymers by Two-Step Swelling and Polymerization. In: Martín-Esteban, A. (eds) Molecularly Imprinted Polymers. Methods in Molecular Biology, vol 2359. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1629-1_1
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DOI: https://doi.org/10.1007/978-1-0716-1629-1_1
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