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Inorganic Nanostructures for Brain Tumor Management

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Nanotherapy for Brain Tumor Drug Delivery

Part of the book series: Neuromethods ((NM,volume 163))

Abstract

The nanoparticles have been widely investigated as therapeutic agents for cancer treatments in biomedical fields due to their unique physical/chemical properties, versatile synthetic strategies, easy surface functionalization, and excellent biocompatibility. Even though the advancement of certain treatment techniques is available for the diagnosis of the tumor, still the blood-brain barrier is the obstruction to the delivery of drug molecules to the tumor cells in the central nervous system (CNS) and brain parenchyma. Though nano enabled therapy make promise to deliver the anticancer drugs to cross the blood-brain barrier (BBB). This chapter focuses on the synthesis techniques and advanced characterization techniques adopted to design and develop inorganic nanostructures. Various inorganic nanostructure-based cancer therapeutic agents, including gold nanoparticles, magnetic nanoparticles, carbon nanotube, earth metal oxide nanoparticles, and other nanostructures, have also been discussed. Related challenges with this research area and future prospect are also discussed herein.

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Acknowledgments

Authors do acknowledge respective department and institution for providing resources and facilities.

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Authors and Affiliations

  1. Department of Chemical Engineering, Faculty of Engineering, Jazan University, Jazan, Kingdom of Saudi Arabia

    Mohd Imran

  2. Emergency Medical Services Department, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia

    Awais Ahmed Abrar Ahmed

  3. National Center for NanoBioElectronics, West Hollywood, CA, USA

    Babak Kateb

  4. California Neurosurgical Institute, Los Angeles, CA, USA

    Babak Kateb

  5. Brain Mapping Foundation, West Hollywood, CA, USA

    Babak Kateb

  6. Society for Brain Mapping and Therapeutics, West Hollywood, CA, USA

    Babak Kateb

  7. Center for Personalized Nanomedicine, Institute of NeuroImmune Pharmacology, Department of Immunology and NanoMedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA

    Ajeet Kaushik

  8. NanoBioTech Laboratory, Department of Natural Sciences, Division of Sciences, Art, & Mathematics, Florida Polytechnic University, Lakeland, FL, USA

    Ajeet Kaushik

Authors
  1. Mohd Imran
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  2. Awais Ahmed Abrar Ahmed
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  3. Babak Kateb
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  4. Ajeet Kaushik
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Editor information

Editors and Affiliations

  1. CONRAD / Eastern Virginia Medical School, Arlington, VA, USA

    Vivek Agrahari

  2. Department of Neurosurgery and Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA

    Anthony Kim

  3. Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Science Center, Oklahoma City, OK, USA

    Vibhuti Agrahari

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Imran, M., Ahmed, A.A.A., Kateb, B., Kaushik, A. (2021). Inorganic Nanostructures for Brain Tumor Management. In: Agrahari, V., Kim, A., Agrahari, V. (eds) Nanotherapy for Brain Tumor Drug Delivery. Neuromethods, vol 163. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1052-7_6

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  • DOI: https://doi.org/10.1007/978-1-0716-1052-7_6

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