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Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction: results from J-MINUET

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Abstract

Previous studies have demonstrated that use of intravascular ultrasound (IVUS) during percutaneous coronary intervention (PCI) was associated with lower incidence of death, myocardial infarction, and target vessel revascularization. Recently, optical coherence tomography (OCT) has emerged as an alternative intravascular imaging device with better resolution. The aim of this study was to investigate frequency and prognostic impact of IVUS or OCT-guided PCI during urgent revascularization for acute myocardial infarction diagnosed by the universal definition. A total of 2788 patients who underwent urgent PCI were selected from a multicenter, Japanese registry of acute myocardial infarction diagnosed by universal definition (J-MINUET). Frequency, clinical characteristics and prognostic impact of the IVUS-, or OCT- guided PCI were investigated. Clinical endpoint was in-hospital death. Angiography-, IVUS-, and OCT-guided urgent PCI were performed in 689 (24.7%), 1947 (69.8%), and 152 (5.5%) patients. In-hospital death in each group was 10.4%, 5.1%, and 3.3%, respectively (P < 0.01). By univariate and multivariate logistic regression analysis, IVUS-guided PCI (vs. angiography-guided PCI, OR 0.49, 95% CI 0.30–0.81, P = 0.006) was a significant independent predictor of in-hospital death. Intravascular imaging guided-PCI was frequently adopted during urgent PCI for acute myocardial infarction diagnosed by universal definition and was associated with better in-hospital survival.

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Acknowledgments

This study was supported by the Intramural Research Fund, Grant number 23-4-5, for Cardiovascular Diseases of the National Cerebral and Cardiovascular Center. The authors thank all the enrolled patients, participating cardiologists, medical and other staffs who have contributed to this study. The J-MINUET investigators are listed in Appendix. J-MINUET Investigators: Masaharu Ishihara, Hyogo College of Medicine; Ogawa Hisao, National Cerebral and Cardiovascular Center, Kumamoto University Graduate School of Medical Sciences; Nobuaki Kokubu, Sapporo Medical University; Tadaya Sato, Akita Medical Center; Teruo Inoue, Dokkyo Medical University; Shigeru Oshima, Gunma Prefectural Cardiovascular Center; Hiroshi Funayama, Saitama Medical Center Jichi Medical University; Ken Kozuma, Hiroyuki Kyono, Teikyo University; Wataru Shimizu, Nippon Medical School; Satoru Suwa, Juntendo University Shizuoka Hospital; Kengo Tanabe, Mitsui Memorial Hospital; Tetsuya Tobaru, Sakakibara Heart Institute; Kazuo Kimura, Yokohama City University Medical Center; Junya Ako, Kitasato University; Mafumi Owa, Suwa Red Cross Hospital; Yasuhiro Morita, Ogaki Municipal Hospital; Yukio Ozaki, Fujita Health University; Satoshi Yasuda, Teruo Noguchi, Masashi Fujino, National Cerebral and Cardiovascular Center, Junichi Kotani, Osaka University Graduate School of Medicine; Takashi Morita, Osaka General Medical Center; Atsunori Okamura, Sakurabashi Watanabe Hospital; Yoshihiko Saito, Nara Medical University; Masaaki Uematsu, Kansai Rosai Hospital; Hiroyuki Okura, Kawasaki Medical School; Atsushi Hirohata, The Sakakibara Heart Institute of Okayama; Yasuharu Nakama, Hiroshima City Hospital; Keijiro Saku, Fukuoka University School of Medicine; Seiji Hokimoto, Kumamoto University Graduate School of Medical Sciences; Koichi, Saiseikai Kumamoto Hospital; Kazuteru Fujimoto, National Hospital Organization Kumamoto Medical Center; Yoshisato Shibata, Miyazaki Medical Association Hospital; Kazuhito Hirata, Okinawa Prefectural Chubu Hospital. Yoshihiro Miyamoto, Kunihiro Nishimura, Michikazu Nakai, National Cerebral and Cardiovascular Center.

Funding

Grant This study was supported by the Intramural Research Fund, Grant number 23-4-5, for Cardiovascular Diseases of the National Cerebral and Cardiovascular Center.

Author information

Authors and Affiliations

  1. Department of Cardiovascular Medicine, Nara Medical University, 840 Shijyo-cho, Kashihara, Nara, Japan

    Hiroyuki Okura, Yoshihiko Saito & Tsunenari Soeda

  2. Cardiovascular Center, Saiseikai Kumamoto Hospital, Kumamoto, Japan

    Koichi Nakao

  3. Department of Cardiology, Fujita Health University, Toyoake, Japan

    Yukio Ozaki

  4. Cardiovascular Center, Yokohama City University Medical Center, Yokohama, Japan

    Kazuo Kimura

  5. Department of Cardiovascular Medicine, Kitasato University, Sagamihara, Japan

    Junya Ako

  6. Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan

    Teruo Noguchi, Satoshi Yasuda, Kunihiro Nishimura & Yoshihiro Miyamoto

  7. Department of Cardiology, Juntendo University Shizuoka Hospital, Shizuoka, Japan

    Satoru Suwa

  8. Department of Cardiology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan

    Kazuteru Fujimoto

  9. Department of Cardiology, Hiroshima City Hospital, Hiroshima, Japan

    Yasuharu Nakama

  10. Division of Cardiology, Osaka General Medical Center, Osaka, Japan

    Takashi Morita

  11. Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan

    Wataru Shimizu

  12. Department of Cardiology, The Sakakibara Heart Institute of Okayama, Okayama, Japan

    Atsushi Hirohata

  13. Department of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan

    Yasuhiro Morita

  14. Department of Cardiovascular Medicine, Dokkyo Medical University, Tochigi, Japan

    Teruo Inoue

  15. Department of Cardiology, Sakurabashi Watanabe Hospital, Osaka, Japan

    Atsunori Okamura

  16. Cardiovascular Center, Kansai Rosai Hospital, Amagasaki, Japan

    Masaaki Uematsu

  17. Department of Cardiology, Okinawa Prefectural Chubu Hospital, Uruma, Japan

    Kazuhito Hirata

  18. Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan

    Kengo Tanabe

  19. Department of Cardiology, Miyazaki Medical Association Hospital, Miyazaki, Japan

    Yoshisato Shibata

  20. Department of Cardiovascular Medicine, Suwa Red Cross Hospital, Suwa, Japan

    Mafumi Owa

  21. Department of Cardiovascular Medicine, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan

    Kenichi Tsujita

  22. Division of Coronary Artery Disease, Hyogo College of Medicine, Nishinomiya, Japan

    Masaharu Ishihara

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  1. Hiroyuki Okura
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  2. Yoshihiko Saito
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  3. Tsunenari Soeda
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  5. Yukio Ozaki
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  6. Kazuo Kimura
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  7. Junya Ako
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  8. Teruo Noguchi
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  9. Satoshi Yasuda
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  11. Kazuteru Fujimoto
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  13. Takashi Morita
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  14. Wataru Shimizu
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  15. Atsushi Hirohata
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  18. Atsunori Okamura
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  19. Masaaki Uematsu
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  23. Mafumi Owa
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  25. Kunihiro Nishimura
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  26. Yoshihiro Miyamoto
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  27. Masaharu Ishihara
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Consortia

The J-MINUET investigators

  • Masaharu Ishihara
  • , Ogawa Hisao
  • , Nobuaki Kokubu
  • , Tadaya Sato
  • , Teruo Inoue
  • , Shigeru Oshima
  • , Hiroshi Funayama
  • , Ken Kozuma
  • , Hiroyuki Kyono
  • , Wataru Shimizu
  • , Satoru Suwa
  • , Kengo Tanabe
  • , Tetsuya Tobaru
  • , Kazuo Kimura
  • , Junya Ako
  • , Mafumi Owa
  • , Yasuhiro Morita
  • , Yukio Ozaki
  • , Satoshi Yasuda
  • , Teruo Noguchi
  • , Masashi Fujino
  • , Junichi Kotani
  • , Takashi Morita
  • , Atsunori Okamura
  • , Yoshihiko Saito
  • , Masaaki Uematsu
  • , Hiroyuki Okura
  • , Atsushi Hirohata
  • , Yasuharu Nakama
  • , Keijiro Saku
  • , Seiji Hokimoto
  • ,  Koichi
  • , Kazuteru Fujimoto
  • , Yoshisato Shibata
  • , Kazuhito Hirata
  • , Yoshihiro Miyamoto
  • , Kunihiro Nishimura
  •  & Michikazu Nakai

Corresponding author

Correspondence to Hiroyuki Okura.

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Conflict of interest

The authors report no relationships that could be construed as a conflict of interest.

Additional information

The J-MINUET investigators are listed in Acknowledgements.

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Okura, H., Saito, Y., Soeda, T. et al. Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction: results from J-MINUET. Heart Vessels 34, 564–571 (2019). https://doi.org/10.1007/s00380-018-1285-3

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  • DOI: https://doi.org/10.1007/s00380-018-1285-3

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