Summary
Residual insulin secretion and islet-cell antibodies were studied in 399 insulin-dependent diabetics with age at onset of between 10–19.9 years (248 patients) or 30–39.9 years (151 patients). We found the prevalence of islet-cell antibodies to be independent of residual beta-cell function as measured by serum C-peptide and age at onset. The cause and role of the persistence of islet-cell antibodies in insulin-dependent diabetics remain obscure.
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Madsbad, S., Bottazzo, G.F., Cudworth, A.G. et al. Islet-cell antibodies and beta-cell function in insulin-dependent diabetics. Diabetologia 18, 45–47 (1980). https://doi.org/10.1007/BF01228301
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DOI: https://doi.org/10.1007/BF01228301