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LIPID MAPS: Tools and Databases

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Encyclopedia of Lipidomics

The Lipid Metabolites and Pathways Strategy (LIPID MAPS) initiative is a consortium intended to acquire an in-depth knowledge of lipid structure and function which was initiated in 2003 by a U.S. National Institute of General Medical Sciences Large Scale Collaborations “Glue” grant. As such, the consortium works on various solutions arising in the analysis of lipids. The core of LIPID MAPS is formed by a comprehensive classification system for lipids (Fahy et al. 2005, 2009) which was developed by the International Lipids Classification and Nomenclature Committee (ILCNC). LIPID MAPS chose a chemistry-based approach where lipid species are classified into eight categories (fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides), subsequent classes, and subclasses. The assignment to these categories/classes is reflected in the LIPID MAPS identifier (LM ID) which consists of a 12-character representation, where the...

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Abbreviations

MS:

mass spectrometry

m/z:

mass to charge ratio

LIPID MAPS:

Lipid Metabolites and Pathways Strategy; i.e. a consortium intended to acquire in-depth knowledge of lipid structure and function

ILCNC:

International Lipids Classification and Nomenclature Committee

PubChem:

database of chemical molecules and their activities

PubChem SID:

PubChem substance identification number

LM ID:

LIPID MAPS identifier

PHP:

a server-side scripting language

InChi:

International Chemical Identifier, i.e. an identifier for chemical substances

KEGG:

Kyoto Encyclopedia of Genes and Genomes

HMDB:

Human Metabolome Database, i.e. a database containing information about small molecules and metabolites found in the human body

YMDB:

Yeast Metabolome Database, i.e. a database containing information about small molecules and metabolites found in Baker’s yeast

ChEBI:

Chemical Entities of Biological Interest, i.e. a database and ontology for small molecules

GO:

Gene Ontology, i.e. an initiative to provide a uniform ontology for genes and gene products

EC number:

Enzyme Commission number

InterPro:

database for protein families and domains

PRINTS:

a database containing protein fingerprints, i.e. a group of conserved motifs

Pfam:

a database for protein families including their annotations

SMART:

Simple Modular Architecture Research Tool, i.e. a database for protein domains

Swiss-Prot:

manually annotated and reviewed protein sequence database

VANTED:

Visualization and Analysis of Networks containing Experimental Data, i.e. a network visualization tool

References

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Authors and Affiliations

  1. Computational Biotechnology and Bioinformatics Group, Institute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14/V, 8010, Graz, Austria

    Jürgen Hartler

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  1. Jürgen Hartler
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Correspondence to Jürgen Hartler .

Editor information

Editors and Affiliations

  1. Yong Loo Lin School of Medicine Centre for Life Sciences, Singapore, Singapore

    Markus R. Wenk

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Hartler, J. (2015). LIPID MAPS: Tools and Databases. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_11-1

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  • DOI: https://doi.org/10.1007/978-94-007-7864-1_11-1

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  • Online ISBN: 978-94-007-7864-1

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