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Abuse Liability Evaluation

  • Living reference work entry
  • First Online:
Encyclopedia of Psychopharmacology

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Synonyms

Abuse potential

Definition

The abuse liability of a drug or a class of drugs is their propensity to be abused and produce adverse public health consequences. Although much of what constitutes abuse liability of a drug arises from the pharmacological properties of the drug itself (i.e., its ability to produce psychoactive effects associated with risk for abuse and/or addiction, also known as abuse potential), it can also be affected by social and cultural factors and may change from time to time as one drug or class of drug gains popularity in a particular culture. Individual products, even those containing the same generic drug, can differ in abuse liability, which may be determined by the specific formulation, the indication for which it is used, and other things, such as its market penetration and price.

Current Concepts and State of Knowledge

Background

One of the principal public health strategies for drug abuse prevention is to place regulatory controls on the...

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References

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Author information

Authors and Affiliations

  1. Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Room 746A Smith Building, 410N 12th Street, PO Box 980310, Richmond, VA, 23298-0310, USA

    Robert L. Balster

  2. Department of Behavioral Sciences, Center on Drug and Alcohol Research, College of Medicine, University of Kentucky, Lexington, KY, 40506-9983, USA

    Sharon L. Walsh

Authors
  1. Robert L. Balster
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  2. Sharon L. Walsh
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Corresponding author

Correspondence to Robert L. Balster .

Editor information

Editors and Affiliations

  1. Section of Behavioural Pharmacology, King's College London Institute of Psychiatry P049, London, United Kingdom

    Ian P. Stolerman

  2. Brown Medical School, Butler Hospital, Providence, Rhode Island, USA

    Lawrence H. Price

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© 2013 Springer-Verlag Berlin Heidelberg

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Balster, R.L., Walsh, S.L. (2013). Abuse Liability Evaluation. In: Stolerman, I., Price, L. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27772-6_30-2

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  • DOI: https://doi.org/10.1007/978-3-642-27772-6_30-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27772-6

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