Definition
A melatonin MT1 and MT2 receptor agonist and 5-HT2C antagonist, known to be effective in acute treatment and relapse prevention in major depressive disorder, it also has proven efficacy in Generalized Anxiety Disorder. It seems better tolerated than some SSRIs and venlafaxine, with fewer treatment-emergent side effects and a reduced burden of discontinuation symptoms.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Baldwin, D.S. (2010). Agomelatine. In: Stolerman, I.P. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68706-1_622
Download citation
DOI: https://doi.org/10.1007/978-3-540-68706-1_622
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-68698-9
Online ISBN: 978-3-540-68706-1
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences