Abstract
A 16-year-old male adolescent complained of a sudden headache with no known cause or trigger, which spontaneously got resolved. Three days later he had another episode of headache and lost consciousness. He was brought to our emergency room, where cardiopulmonary resuscitation was required (Hunt and Hess V). CT showed a massive subarachnoid hemorrhage (SAH) with blood in the basal cisterns (Fisher 4). A CTA failed to opacify the intracranial vasculature, thought to be related to poor timing of the contrast bolus. Thorax CT showed massive aspiration. DSA of the carotid arteries and the left vertebral artery revealed an aneurysm of the basilar artery bifurcation and a standstill of the cerebral circulation beyond the basal arteries. The basilar artery bifurcation aneurysm was considered the most likely cause of the massive SAH. Another DSA examination 30 min later showed the same result. Intravital brain death was diagnosed and documented. After another 2 days of intensive care, the lung, liver, pancreas, heart valves, cornea, and kidneys were harvested and transplanted. The criteria for the diagnosis of intravital brain death are the main topic of this chapter.
References
Drake M, Bernard A, Hessel E. Brain death. Surg Clin North Am. 2017;97(6):1255–73. https://doi.org/10.1016/j.suc.2017.07.001.
European Directorate for the Quality of Medicines and HealthCare (EDQM). Guide to the quality and safety of organs for transplantation. 7th ed. Strasbourg; 2018. ISBN 978-92-871-8596-9
Etminan N, Chang HS, Hackenberg K, de Rooij NK, Vergouwen MDI, Rinkel GJE, Algra A. Worldwide incidence of aneurysmal subarachnoid hemorrhage according to region, time period, blood pressure, and smoking prevalence in the population: a systematic review and meta-analysis. JAMA Neurol. 2019;76(5):588–97. https://doi.org/10.1001/jamaneurol.2019.0006.
Gastala J, Fattal D, Kirby PA, Capizzano AA, Sato Y, Moritani T. Brain death: radiologic signs of a non-radiologic diagnosis. Clin Neurol Neurosurg. 2019;185:105465. https://doi.org/10.1016/j.clineuro.2019.105465.
Lanfermann H. Angiographische Verfahren zur Feststellung des zerebralen Zirkulationsstillstandes [Angiographic procedures for determination of cessation of cerebral circulation]. Nervenarzt. 2016;87(2):144–8. https://doi.org/10.1007/s00115-015-0047-z. German
Petridis AK, Kamp MA, Cornelius JF, Beez T, Beseoglu K, Turowski B, Steiger HJ. Aneurysmal subarachnoid hemorrhage. Dtsch Arztebl Int. 2017;114(13):226–36. https://doi.org/10.3238/arztebl.2017.0226.
Richtlinie gemäß § 16 Abs. 1 S. 1 Nr. 1 TPG für die Regeln zur Feststellung des Todes nach § 3 Abs. 1 S. 1 Nr. 2 TPG und die Verfahrensregeln zur Feststellung des endgültigen, nicht behebbaren Ausfalls der Gesamtfunktion des Großhirns, des Kleinhirns und des Hirnstamms nach § 3 Abs. 2 Nr. 2 TPG, Vierte Fortschreibung. Dtsch Ärztebl | 30. März 2015 | https://doi.org/10.3238/arztebl.2015.rl_hirnfunktionsausfall_01.
Sawicki M, Sołek-Pastuszka J, Chamier-Ciemińska K, Walecka A, Bohatyrewicz R. Accuracy of computed tomographic perfusion in diagnosis of brain death: a prospective cohort study. Med Sci Monit. 2018;24:2777–85. https://doi.org/10.12659/MSM.906304.
Taylor T, Dineen RA, Gardiner DC, Buss CH, Howatson A, Pace NL. Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death. Cochrane Database Syst Rev. 2014;2014(3):CD009694. https://doi.org/10.1002/14651858.CD009694.pub2.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this entry
Cite this entry
Henkes, H., Wagner, S., Melville, C., Khanafer, A., Ganslandt, O., Bäzner, H. (2020). Basilar Artery Bifurcation Aneurysm: Rupture of a So-Far Undiagnosed Basilar Artery Bifurcation Aneurysm in an Adolescent, Resulting in Intravital Brain Death; Establishing Brain Death Diagnosis by Imaging. In: Henkes, H., Lylyk, P., Ganslandt, O. (eds) The Aneurysm Casebook. Springer, Cham. https://doi.org/10.1007/978-3-319-70267-4_181-1
Download citation
DOI: https://doi.org/10.1007/978-3-319-70267-4_181-1
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-70267-4
Online ISBN: 978-3-319-70267-4
eBook Packages: Springer Reference MedicineReference Module Medicine