Synonyms
Bronchial cyst
Definition
Bronchogenic cyst is a developmental anomaly formed from the primitive foregut that gives rise to pharynx, lower respiratory tract, and upper gastrointestinal tract. It is formed as an abnormal budding of the tracheobronchial tree during embryogenesis. It moves with respiration. They are usually asymptomatic but can cause symptoms if compressing trachea, bronchi, or esophagus.
Clinical Features
Incidence
Rare but the most common of all foregut cysts.
Age
Any age. Usually found in young adults.
Sex
Males and females are equally affected.
Site
Anterior mediastinum. May also be found in other parts of mediastinum and in the lung parenchyma.
Treatment
Surgery (for symptomatic cysts). Sometimes percutaneous needle aspiration is performed.
Outcome
Good.
Macroscopy
Unilocular or sometimes multilocular cyst with smooth inner and outer surface; wall of the cyst can vary in thickness. Often filled with mucus.
Microscopy
A cyst is lined by pseudostratified...
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References and Further Reading
Plaza, J. A., Moran, C. A., & Suster, S. (2010). Thymus and mediastinum. In P. Gattuso, V. B. Reddy, O. David, D. J. Spitz, & M. H. Haber (Eds.), Differential diagnosis in surgical pathology (pp. 283–284). Philadelphia: Saunders Elsevier.
Shimosato, Y., Mukai, K., & Matsuno, Y. (2010). Bronchogenic cyst. In S. G. Silverberg (Ed.), AFIP atlas of tumor pathology. Tumors of the mediastinum (pp. 305–306). Washington, DC: American Registry of Pathology.
Wick, M. R. (2005). Cystic lesions of the mediastinum. Seminars in Diagnostic Pathology, 22, 241–253.
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Brcic, I. (2018). Bronchogenic Cyst, Mediastinal. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_7
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DOI: https://doi.org/10.1007/978-3-319-66796-6_7
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