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Biomediated Atomic Metal Nanoclusters: Synthesis and Theory

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  • First Online:
Handbook of Nanoparticles

Abstract

Fluorescent metal nanoclusters are an emerging class of multifunctional materials engineered at the single-atom level, with dimensions approaching the Fermi wavelength of electrons that offer competitive functionalities of traditional semiconductor QDs including tunable emission, ease of conjugation, extended photostability, and high quantum yield. With the additional advantages of being composed of nontoxic/biocompatible materials, function with a fraction of the metal content, greatly reduced size for enhanced cellular uptake, opportunity for two-photon absorption at biologically relevant wavelengths, and demonstrated renal evacuation efficacy for in vivo applications, metal nanoclusters hold substantial promise. More recently the development of hybrid atomic cluster synthesis routes has expanded the materials’ multifunctional capabilities. This chapter will summarize the current high-yield synthesis and functionalization strategies for producing monodisperse pure metal and hybrid nanocluster materials from both wet chemistry and newly developed biomediated nanocluster synthesis methodologies, involving protein and DNA hosts. The role of the bio-host and surface functional groups on the nanoclusters formation, stability, and physical properties will be detailed through recent experimental and theoretical simulation efforts.

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Authors and Affiliations

  1. Weapons and Materials Research Directorate, US Army Research Laboratory, Aberdeen Proving Grounds, MD, USA

    Mark H. Griep, Abby L. West, Michael S. P. Sellers, Molleshree Karna & Nabila Hoque

  2. United States Military Academy, West Point, NY, USA

    Edric Zhan

Authors
  1. Mark H. Griep
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  2. Abby L. West
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  3. Michael S. P. Sellers
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  4. Molleshree Karna
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  5. Edric Zhan
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  6. Nabila Hoque
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Correspondence to Mark H. Griep .

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Editors and Affiliations

  1. Materials Engineering, Tarbiat Modares University, Tehran, Iran

    Mahmood Aliofkhazraei

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Griep, M.H., West, A.L., Sellers, M.S., Karna, M., Zhan, E., Hoque, N. (2015). Biomediated Atomic Metal Nanoclusters: Synthesis and Theory. In: Aliofkhazraei, M. (eds) Handbook of Nanoparticles. Springer, Cham. https://doi.org/10.1007/978-3-319-13188-7_33-1

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  • DOI: https://doi.org/10.1007/978-3-319-13188-7_33-1

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  • Online ISBN: 978-3-319-13188-7

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