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Orthotopic Liver Transplantation: Indications and Contraindications

  • Reference work entry
  • First Online:
Contemporary Liver Transplantation

Part of the book series: Organ and Tissue Transplantation ((OTT))

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Abstract

At the beginning of the third millennium, liver transplantation (LT) has turned from dream into a reality. Thomas E. Starzl, who first performed LT in March 1963, and many of his scholars allowed to live one of the most extraordinary adventures of modern medicine. Twenty years later, in 1983, the National Institute of Health Consensus Development Conference concluded that LT was “a promising alternative to current therapy in the management of late phase of several forms of serious liver diseases” and that it had the potential to become a “clinical service” as opposed to an experimental procedure. Half a century later, LT progressed at high speed resulting in a worldwide, curative, treatment of more than 50 different liver as well as liver-based diseases. Today the 250,000 mark has been reached. This chapter gives a detailed overview of all the different aspects of this medical adventure, stressing thereby also the last innovations and forthcoming revolutions to expect.

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Authors and Affiliations

  1. Starzl Abdominal Transplant Unit, Department of Abdominal and Transplantation Surgery, University Hospitals St. Luc, Université catholique Louvain (UCL), Brussels, Belgium

    Quirino Lai & Jan Lerut

  2. Transplant Unit, Department of Surgery, San Salvatore Hospital, University of L’Aquila, L’Aquila, Italy

    Quirino Lai & Samuele Iesari

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  1. Quirino Lai
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  2. Samuele Iesari
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  3. Jan Lerut
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Correspondence to Jan Lerut .

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Editors and Affiliations

  1. Nicoletti Family Professor of Transplant Surgery, Director, Jefferson Transplant Institute, Director, Division of Transplantation, Surgical Director, Kimmel Cancer Center – Jefferson Liver Tumor Center, Sidney Kimmel Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

    Cataldo Doria

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Lai, Q., Iesari, S., Lerut, J. (2017). Orthotopic Liver Transplantation: Indications and Contraindications. In: Doria, C. (eds) Contemporary Liver Transplantation. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-07209-8_40

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