Definition
Antihistamines are a class of drugs that inhibit the physiological effects of histamine and are widely used in the treatment of allergic and related immunological diseases.
Introduction
In 1910–1911 the physiological and pathological effects of histamine were first described. There are two major groups of antihistamines: those which block H1 receptors (H1 antihistamines) and those which block the action of histamine at H2 receptors (H2 antihistamines). H1 antihistamines are widely used in the treatment of allergic and related immunological diseases. H2 blockers inhibit the secretion of hydrochloric acid in the stomach and are considered only peripherally in this review.
Since their introduction in the 1940s, the H1 antihistamines have come into common use for the treatment of allergic diseases. Most importantly, the H1 antihistamines...
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Murad, A., Katelaris, C.H., Graham, G.G. (2013). Antihistamines. In: Parnham, M. (eds) Compendium of Inflammatory Diseases. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-0620-6_8-1
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DOI: https://doi.org/10.1007/978-3-0348-0620-6_8-1
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