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Definition

Munc13 is a presynaptic protein with an essential role in making synaptic vesicles competent for fusion with the membrane (synaptic vesicle priming). The priming activity appears to be activated by diacylglycerol, and is thought to be mediated by binding of Munc13 to syntaxin I.

Protein and Membrane Transport in Eukaryotic Cells

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© 2006 Springer-Verlag

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(2006). Munc13. In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-29623-9_7920

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