Definition
Focal adhesion complex is a multiprotein complex that is transiently formed inside the cell in response to ligand binding to integrins. FAC is attached to actin filaments that allow the cell to exert the mechanical tension required for cell movement. FAC can also activate other downstream signaling pathways that can alter cell migration.
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© 2011 Springer-Verlag Berlin Heidelberg
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(2011). FAC. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_2089
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DOI: https://doi.org/10.1007/978-3-642-16483-5_2089
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-16482-8
Online ISBN: 978-3-642-16483-5
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