Skip to main content
SpringerLink
Log in

Hepatitis A Virus

Molecular Detection and Typing

  • Protocol
Public Health Microbiology

Part of the book series: Methods in Molecular Biology ((MIMB,volume 268))

Abstract

Hepatitis A virus (HAV) infection is the leading cause of viral hepatitis throughout the world (1). HAV infection is mainly propagated via the fecal-oral route (2), and waterborne (3) and foodborne (4–8) outbreaks of the disease have been reported.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Protocol
USD 49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Centers for Disease Control and Prevention (1995) Hepatitis Surveillance Report No. 56. Centers for Disease Control and Prevention, Atlanta, GA.

    Google Scholar 

  2. Mast, E. E. and Alter, M. J. (1993) Epidemiology of viral hepatitis: an overview. Sem. Virol. 4, 273–283.

    Article  Google Scholar 

  3. Bosch, A., Lucena, F., Díez, J. M., Gajardo, R., Blasi, M., and Jofre, J. (1991) Human enteric viruses and indicator microorganisms in a water supply associated with an outbreak of infectious hepatitis. J. Am. Water Works Assoc. 83, 80–83.

    Google Scholar 

  4. Bosch, A., Sánchez, G., Le Guyader, F., Vanaclocha, H., Haugarreau, L., and Pintó, R.M. (2001) Human enteric viruses in coquina clams associated with a large hepatitis A outbreak. Wat. Sci. Tech. 43, 61–65.

    CAS  Google Scholar 

  5. Halliday, M. L., Kang, L.-Y., Zhou, T.-K., et al. (1991) An epidemic of hepatitis A attributable to the ingestion of raw clams in Shanghai, China. J. Infect. Dis. 164, 852–859.

    PubMed  CAS  Google Scholar 

  6. Mele, A., Rastelli, M. G., Gill, O. N., et al. (1989) Recurrent epidemic hepatitis A associated with the consumption of raw shellfish, probably controlled through public health mesures. Am. J. Epidemiol. 130, 540–546.

    PubMed  CAS  Google Scholar 

  7. Reid, T. M. S. and Robinson, H. G. (1987) Frozen raspberries and hepatitis A. Epidemiol. Infect. 98, 109–112.

    Article  PubMed  CAS  Google Scholar 

  8. Rosemblum, L. S., Mirkin, I. R., Allen, D. T., Safford, S., and Hadler, S. C. (1990) A multistate outbreak of hepatitis A traced to commercially distributed lettuce. Am. J. Public Health 80, 1075–1080.

    Article  Google Scholar 

  9. Hollinger, F. B. and Emerson, S. U. (2001) Hepatitis A virus. In: Fields Virology, 4th ed., vol. 1 (Fields, B. N., Knipe. D. M., Howley, P. M., eds.). Lippincott-Williams & Wilkins, New York, pp. 799–840.

    Google Scholar 

  10. Robertson, B. H., Jansen, R. W., Khanna, B., et al. (1992) Genetic relatedness of hepatitis A virus strains recovered from different geographical regions. J. Gen. Virol. 73, 1365–1377.

    Article  PubMed  CAS  Google Scholar 

  11. Taylor, M. B. (1997) Molecular epidemiology of South African strains of hepatitis A virus: 1982–1996. J. Med. Virol. 51, 73–79.

    Article  Google Scholar 

  12. Graff, J., Richards, O. C., Swiderek, K. M., et al. (1999) Hepatitis A virus capsid protein VP1 has a heterogeneous C terminus. J. Virol. 73, 6015–6023.

    PubMed  CAS  Google Scholar 

  13. Martin, A., Benichou, D., Chao, S. F., Cohen, L. M., and Lemon, S. M. (1999) Maturation of the hepatitis A virus capsid protein VP1 is not dependent on processing by the 3Cpro proteinase. J. Virol. 73, 6220–6227.

    PubMed  CAS  Google Scholar 

  14. Gajardo, R., Bouchriti, N., Pintó, R. M., and Bosch, A. (1995) Genotyping of rotaviruses isolated from sewage. Appl. Environ. Microbiol. 61, 3460–3462.

    PubMed  CAS  Google Scholar 

  15. Boom, R., Sol, C. J. A., Salimans, M. M. M., Jansen, C. L., Wertheim-van Dillen, P. M. E., and Van der Noordaa, J. (1990) Rapid and simple method for purification of nucleic acids. J. Clin. Microbiol. 28, 495–503.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Enteric Virus Laboratory, Department of Microbiology, School of Biology, University of Barcelona, Barcelona, Spain

    Glòria Sánchez, Cristina Villena, Albert Bosch & Rosa M. Pintó

Authors
  1. Glòria Sánchez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Cristina Villena
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Albert Bosch
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rosa M. Pintó
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Planta Piloto de Procesos Industriales Microbiológicos, (PROIMI)-CONICET, San Miguel de Tucumán, Argentina

    John F. T. Spencer  & Alicia L. Ragout de Spencer  & 

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Humana Press Inc.Totowa, NJ

About this protocol

Cite this protocol

Sánchez, G., Villena, C., Bosch, A., Pintó, R.M. (2004). Hepatitis A Virus. In: Spencer, J.F.T., Ragout de Spencer, A.L. (eds) Public Health Microbiology. Methods in Molecular Biology, vol 268. Humana Press. https://doi.org/10.1385/1-59259-766-1:103

Download citation

  • DOI: https://doi.org/10.1385/1-59259-766-1:103

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-117-2

  • Online ISBN: 978-1-59259-766-6

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics

Search

Navigation