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Analysis of Bcr-Abl Function Using an In Vitro Embryonic Stem Cell Differentiation System

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Embryonic Stem Cells

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 185))

Abstract

Numerous causative genes involved in human cancers, such as leukemias and lymphomas, have been identified (1). Considerable evidence has accumulated showing that disruptions of these genes can affect hematopoietic cell differentiation and growth. However, it remains largely unknown how these molecules function directly in hematopoietic stem cells.

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© 2002 Humana Press Inc., Totowa, NJ

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Era, T., Wong, S., Witte, O.N. (2002). Analysis of Bcr-Abl Function Using an In Vitro Embryonic Stem Cell Differentiation System. In: Turksen, K. (eds) Embryonic Stem Cells. Methods in Molecular Biology™, vol 185. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-241-4:83

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  • DOI: https://doi.org/10.1385/1-59259-241-4:83

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-881-3

  • Online ISBN: 978-1-59259-241-8

  • eBook Packages: Springer Protocols

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