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Harmful and Beneficial Activities of Immunological Adjuvants

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Vaccine Adjuvants

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 42))

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Abstract

There are no officially recognized regulations for the design and toxicity testing of adjuvants or adjuvant formulations; the former are also referred to as immunomodulators and immunopotentiators. At the “Immunological Adjuvants and Vaccines” meeting held in Greece in 1988, however, immunoadjuvant researchers discussed experimental toxicological tests that might be used to monitor new immunomodulators (1). The usefulness of these tests for the range of immunomodulators and adjuvant formulations was examined over a 2-yr period and subsequently, at the next NATO meeting in 1990, further recommendations were made (2). Although as yet, no final agreement has been reached and a variety of tests are still in use.

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References

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Author information

Authors and Affiliations

  1. Division of Infection and Immunity, Institute for Biomedical and Life Sciences, University of Glasgow, UK

    Duncan E. S. Stewart-Tull

Authors
  1. Duncan E. S. Stewart-Tull
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Editor information

Editors and Affiliations

  1. Chiron Corporation, Emeryville, CA

    Derek T. O’Hagan

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© 2000 Humana Press Inc.

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Stewart-Tull, D.E.S. (2000). Harmful and Beneficial Activities of Immunological Adjuvants. In: O’Hagan, D.T. (eds) Vaccine Adjuvants. Methods in Molecular Medicine™, vol 42. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-083-7:29

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  • DOI: https://doi.org/10.1385/1-59259-083-7:29

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-735-9

  • Online ISBN: 978-1-59259-083-4

  • eBook Packages: Springer Protocols

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