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Use of Uracil DNA Glycosylase in the Detection of Known DNA Mutations and Polymorphisms

Glycosylase-Mediated Polymorphism Detection (GMPD-Check)

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DNA Repair Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 152))

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Abstract

Detection of known mutations and polymorphisms at specific locations in DNA is now the basis for genetic diagnosis, molecular genotyping, molecular epidemiology, and rapid identification of various traits in eukaryotic and prokaryotic organisms. An optimum system for sequence variation detection needs to offer specificity, sensitivity, flexibility, as well as ease of use and allow rapid and high throughput of samples.

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© 2000 Humana Press Inc.

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Vaughan, P. (2000). Use of Uracil DNA Glycosylase in the Detection of Known DNA Mutations and Polymorphisms. In: Vaughan, P. (eds) DNA Repair Protocols. Methods in Molecular Biology™, vol 152. Humana Press. https://doi.org/10.1385/1-59259-068-3:169

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  • DOI: https://doi.org/10.1385/1-59259-068-3:169

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-643-7

  • Online ISBN: 978-1-59259-068-1

  • eBook Packages: Springer Protocols

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