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Molecular Biological Strategies in the Analysis of Antibiotic Peptide Gene Families

The Use Oligonucleotides as Hybridization Probes

  • Protocol
Antibacterial Peptide Protocols

Part of the book series: Methods In Molecular Biology™ ((MIMB,volume 78))

Abstract

Antibiotic peptides are host defense effector molecules broadly distributed throughout the animal kingdom. Many different families of peptides can be identified based on mature peptide structure or, in some cases, by similar propeptide structure (1). These peptides have been identified in a variety of different cell and tissue types. In several instances, members of a single family of antibiotic peptides are distributed in multiple tissues in a single species. In some species, such as human, more than one family of antibiotic peptide has been identified (2,3). These features afford opportunities to better understand the principles underlying the evolution of this system of host defense.

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Author information

Authors and Affiliations

  1. Research Institute, The Cleveland Clinic Foundation, Cleveland, OH

    Charles L. Bevins

  2. Department of Anatomy, Cell Biology, and Injury Sciences, University of Medicine and Dentistry of New Jersey, Newark, NJ

    Gill Diamond

Authors
  1. Charles L. Bevins
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  2. Gill Diamond
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Editor information

Editors and Affiliations

  1. Emory University School of Medicine, Atlanta, GA

    William M. Shafer

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© 1997 Humana Press Inc.

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Bevins, C.L., Diamond, G. (1997). Molecular Biological Strategies in the Analysis of Antibiotic Peptide Gene Families. In: Shafer, W.M. (eds) Antibacterial Peptide Protocols. Methods In Molecular Biology™, vol 78. Humana Press. https://doi.org/10.1385/0-89603-408-9:151

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  • DOI: https://doi.org/10.1385/0-89603-408-9:151

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-408-2

  • Online ISBN: 978-1-59259-564-8

  • eBook Packages: Springer Protocols

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