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MALDI-TOF Mass Spectrometry-Based SNP Genotyping

  • Protocol
Single Nucleotide Polymorphisms

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 212))

Abstract

Since the invention of dideoxy DNA sequencing (1), the genomes of a number of organisms have been either partially or completely sequenced, including two draft sequences of the human genome (2,3). This offers new opportunities to investigate genetic diversity within and between species. Based on this, an expanding quantity of genetic markers has found widespread use in academic, clinical, and commercial areas.

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Author information

Authors and Affiliations

  1. Sequenom GmbH, Hamburg, Germany

    Niels Storm

  2. Sequenom Inc., San Diego, CA

    Brigitte Darnhofer-Patel

Authors
  1. Niels Storm
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  2. Brigitte Darnhofer-Patel
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Editor information

Editors and Affiliations

  1. Cardiovascular Research Institute and Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA

    Pui-Yan Kwok MD, PhD

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© 2003 Humana Press Inc.

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Storm, N., Darnhofer-Patel, B. (2003). MALDI-TOF Mass Spectrometry-Based SNP Genotyping. In: Kwok, PY. (eds) Single Nucleotide Polymorphisms. Methods in Molecular Biology™, vol 212. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-327-5:241

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  • DOI: https://doi.org/10.1385/1-59259-327-5:241

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-968-1

  • Online ISBN: 978-1-59259-327-9

  • eBook Packages: Springer Protocols

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