Abstract
The heme oxygenase enzymes (HO-1 and HO-2) oxidize heme to biliver-din-IXα (BVIXα), releasing carbon monoxide (CO) and iron (Fig. 1). HO enzymes control the rate of heme degradation and, consequently, also control the redistribution of the heme iron (1). The CO generated from the HO reaction affects signal transduction pathways in neuronal and vascular systems (2).
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Ryter, S.W., Kvam, E., Tyrrell, R.M. (2000). Heme Oxygenase Activity Current Methods and Applications. In: Walker, J.M., Keyse, S.M. (eds) Stress Response. Methods in Molecular Biology™, vol 99. Humana Press. https://doi.org/10.1385/1-59259-054-3:369
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DOI: https://doi.org/10.1385/1-59259-054-3:369
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