Skip to main content
SpringerLink
Log in

Digital Recording of Patch-Clamp Data

  • Protocol
Patch Clamp Techniques

Part of the book series: Springer Protocols Handbooks ((SPH))

  • 4359 Accesses

Abstract

Patch-clamp data, including channel currents and membrane voltage, are usually recorded to a computer via a process known as analog-to-digital conversion. This chapter gives essential information on how to avoid pitfalls and obtain error-free data with optimal resolution.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Sakmann B, Neher E (1995) Single-channel recording, 2nd edn. Plenum, New York

    Book  Google Scholar 

  2. Feynman RP, Hey A (2000) Feynman lectures on computation. Westview Press, New York

    Google Scholar 

  3. Nyquist H (1928) Certain topics in telegraph transmission theory. Trans AIEE 47:617–644 (Reprint as classic paper in: Proc. IEEE 90:280–305, 2002)

    Google Scholar 

  4. Shannon CE (1949) Communication in the presence of noise. Proc Inst Radio Eng 37:10–21 (Reprint as classic paper in: Proc. IEEE 86: 447–457, 1998)

    Google Scholar 

  5. Hino M (1977) Spectrum analysis (in Japanese). Asakura, Tokyo

    Google Scholar 

  6. Bendat JS, Piersol AG (1986) Random data, 2nd edn. Wiley, New York

    Google Scholar 

  7. Hamming RW (1983) Digital filters. Prentice-Hall, Englewood Cliffs

    Google Scholar 

  8. Sigworth FJ, Affolter H, Neher E (1994) Design of EPC-9, a computer-controlled patch-clamp amplifier. 1. Hardware. J Neurosci Methods 56:195–202

    Article  Google Scholar 

  9. Sigworth FJ (1994) Design of EPC-9, a computer-controlled patch-clamp amplifier. 2. Software. J Neurosci Methods 56:203–215

    Article  Google Scholar 

  10. Ogawa H (2006) Sampling theory and Isao Someya: A historical note. Inst Electron Inform Comm Eng Sampl Theor Signal Image Process 5:247–256

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Pharmacology, Department of Biochemistry and Bioinformative Sciences, School of Medicine, University of Fukui, Faculty of Medical Sciences, Fukui, Japan

    Shigeru Morishima

  2. School of Physiology and Pharmacology, Medical Sciences Building, University of Bristol, Bristol, UK

    Andrew F. James

Authors
  1. Shigeru Morishima
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Andrew F. James
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shigeru Morishima .

Editor information

Editors and Affiliations

  1. National Institute for Physiological Sciences National Institutes of Natural Sciences, Okazaki, Aichi, Japan

    Yasunobu Okada

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer

About this protocol

Cite this protocol

Morishima, S., James, A.F. (2012). Digital Recording of Patch-Clamp Data. In: Okada, Y. (eds) Patch Clamp Techniques. Springer Protocols Handbooks. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53993-3_27

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-53993-3_27

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-53992-6

  • Online ISBN: 978-4-431-53993-3

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics

Search

Navigation