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Preparation and Evaluation of Natural Scaffold Materials for Kidney Regenerative Applications

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Organ Regeneration

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1001))

Abstract

Tissue engineering involves the concerted action of biomaterials, cells, and growth factors. Kidney ­regeneration relies on the same combination of ingredients. Here, we describe an example of gelatin-based biomaterial preparation and its evaluation in the context of kidney biocompatibility and integration. This biomaterial manufacturing technique is simple, cost-effective, highly reproducible and the in vivo evaluation procedure highly informative on the biocompatibility and regenerative potential of the tested construct.

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Author information

Authors and Affiliations

  1. Allergan Medical, Medford, MA, USA

    Monica A. Serban

  2. Tengion Inc., Winston-Salem, NC, USA

    Toyin A. Knight & Richard G. Payne

Authors
  1. Monica A. Serban
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  2. Toyin A. Knight
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  3. Richard G. Payne
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Editor information

Editors and Affiliations

  1. Tengion, Inc, Westpoint Blvd. 3929, Winston-Salem, 27103, North Carolina, USA

    Joydeep Basu

  2. Zen Bio, Inc., E Hwy 54 3200, Research Triangle Park, 27709, North Carolina, USA

    John W. Ludlow

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© 2013 Springer Science+Business Media New York

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Serban, M.A., Knight, T.A., Payne, R.G. (2013). Preparation and Evaluation of Natural Scaffold Materials for Kidney Regenerative Applications. In: Basu, J., Ludlow, J. (eds) Organ Regeneration. Methods in Molecular Biology, vol 1001. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-363-3_11

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  • DOI: https://doi.org/10.1007/978-1-62703-363-3_11

  • Published:

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-362-6

  • Online ISBN: 978-1-62703-363-3

  • eBook Packages: Springer Protocols

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