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Pharmacological Models of Parkinson’s Disease in Rodents

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Neurodegeneration

Part of the book series: Methods in Molecular Biology ((MIMB,volume 793))

Abstract

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. Despite the substantial progress that has been achieved, the precise mechanisms involved in the development of this disease are still not fully understood. The most common concepts relate to the genetic background and environmental/toxic effects. A number of model systems have been introduced, which mimic the human disease to varying extents. In this chapter, we introduce some of the most widely accepted protocols of the pharmacological models of Parkinson’s disease.

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Correspondence to Peter Klivenyi .

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Klivenyi, P., Vecsei, L. (2011). Pharmacological Models of Parkinson’s Disease in Rodents. In: Manfredi, G., Kawamata, H. (eds) Neurodegeneration. Methods in Molecular Biology, vol 793. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-328-8_14

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  • DOI: https://doi.org/10.1007/978-1-61779-328-8_14

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-327-1

  • Online ISBN: 978-1-61779-328-8

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