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Accessing and Selecting Genetic Markers from Available Resources

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In Silico Tools for Gene Discovery

Part of the book series: Methods in Molecular Biology ((MIMB,volume 760))

Abstract

The history of genetic markers accurately partitions the progression of molecular genetics into three phases: the RFLP (restriction fragment length polymorphism), microsatellite and SNP (single nucleotide polymorphism) eras. This chapter focuses predominately on the current workhorse, the SNP, though briefly covers the former two and overviews current online databases and portals that act as central repositories as well as hubs to further detailed information. Central gene or disease-based searches are considered and then followed through systematically.

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Author information

Authors and Affiliations

  1. Medical Genomics, UCL Cancer Institute, University College London, London, UK

    Christopher G. Bell

Authors
  1. Christopher G. Bell
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Correspondence to Christopher G. Bell .

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Editors and Affiliations

  1. Royal Prince Alfred Hospital, Dept. of Molecular & Clinical Genetics, University of Sydney, Missenden Road, Camperdown, 2050, New South Wales, Australia

    Bing Yu

  2. Royal Prince Alfred Hospital, Dept. Molecular & Clinical Genetics, University of Sydney, Missenden Road, Camperdown, 2050, New South Wales, Australia

    Marcus Hinchcliffe

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Bell, C.G. (2011). Accessing and Selecting Genetic Markers from Available Resources. In: Yu, B., Hinchcliffe, M. (eds) In Silico Tools for Gene Discovery. Methods in Molecular Biology, vol 760. Humana Press. https://doi.org/10.1007/978-1-61779-176-5_1

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  • DOI: https://doi.org/10.1007/978-1-61779-176-5_1

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-175-8

  • Online ISBN: 978-1-61779-176-5

  • eBook Packages: Springer Protocols

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