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Polyethylenimine Bioconjugates for Imaging and DNA Delivery In Vivo

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Bioconjugation Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 751))

Abstract

Polyamine polymers are among the commonest polymers used in biomedicine. Among polyamine ­polymers, polyethylenimine (PEI) may be used as an efficient delivery vehicle for nucleic acids (DNA, RNA, etc.) or employed as a versatile imaging probe in vivo. In this chapter, the preparation of various PEI bioconjugates will be fully explained and discussed.

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Acknowledgments

The Ministero della Salute and MIUR (Ministero dell’Istruzione, dell’Università e della Ricerca) are gratefully acknowledged for providing financial support for this work. FP also thanks Ernst H.K. Stelzer for support and many interesting discussions.

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Correspondence to Andrea Masotti .

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© 2011 Springer Science+Business Media, LLC

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Masotti, A., Pampaloni, F. (2011). Polyethylenimine Bioconjugates for Imaging and DNA Delivery In Vivo. In: Mark, S. (eds) Bioconjugation Protocols. Methods in Molecular Biology, vol 751. Humana Press. https://doi.org/10.1007/978-1-61779-151-2_10

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  • DOI: https://doi.org/10.1007/978-1-61779-151-2_10

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-150-5

  • Online ISBN: 978-1-61779-151-2

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