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Hepatic Stem Cells

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Hepatocytes

Part of the book series: Methods in Molecular Biology ((MIMB,volume 640))

Abstract

Early studies in hepatocyte turnover and liver regeneration showed that the parenchymal cell, the hepatocyte, was the primary and only cell involved in tissue renewal. However, new studies of liver regeneration, hepatocarcinogenesis, liver transplantation, and various cell lines have shown that a variety of cell types participate in maintaining hepatocyte number and mass and question the dogma of the previous hierarchy of hepatocyte differentiation in vitro and in vivo.

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Brigham and Women’s Hospital, Boston, MA, USA

    Robert E. Schwartz

  2. Interdepartementaal Stamcelinstituut, Leuven, Belgium

    Catherine Verfaillie

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  1. Robert E. Schwartz
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  2. Catherine Verfaillie
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Correspondence to Robert E. Schwartz .

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Editors and Affiliations

  1. INSERM U632, Labo. Physiopathologie Hépatique, Université Montpellier I, rte. Mende 1919, Montpellier, 34293, France

    Patrick Maurel

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Schwartz, R.E., Verfaillie, C. (2010). Hepatic Stem Cells. In: Maurel, P. (eds) Hepatocytes. Methods in Molecular Biology, vol 640. Humana Press. https://doi.org/10.1007/978-1-60761-688-7_9

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