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The FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models

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Metabolic Network Reconstruction and Modeling

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1716))

Abstract

The FASTCORE family is a family of algorithms that are mainly used to build context-specific models but can also be applied to other tasks such as gapfilling and consistency testing. The FASTCORE family has very low computational demands with running times that are several orders of magnitude lower than its main competitors. Furthermore, the models built by the FASTCORE family have a better resolution power (defined as the ability to capture metabolic variations between different tissues, cell types, or contexts) than models from other algorithms.

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Acknowledgments

We would like to thank Dr. Nikos Vlassis for his feedback.

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Authors and Affiliations

  1. Life Sciences Research Unit, University of Luxembourg, Belvaux, Luxembourg

    Maria Pires Pacheco & Thomas Sauter

Authors
  1. Maria Pires Pacheco
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  2. Thomas Sauter
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Corresponding author

Correspondence to Maria Pires Pacheco .

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Editors and Affiliations

  1. Department of Biology, University of Florence, Sesto Fiorentino, Florence, Italy

    Marco Fondi

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Pacheco, M.P., Sauter, T. (2018). The FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models. In: Fondi, M. (eds) Metabolic Network Reconstruction and Modeling. Methods in Molecular Biology, vol 1716. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7528-0_4

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  • DOI: https://doi.org/10.1007/978-1-4939-7528-0_4

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7527-3

  • Online ISBN: 978-1-4939-7528-0

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