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Update on Genomic Databases and Resources at the National Center for Biotechnology Information

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Data Mining Techniques for the Life Sciences

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1415))

Abstract

The National Center for Biotechnology Information (NCBI), as a primary public repository of genomic sequence data, collects and maintains enormous amounts of heterogeneous data. Data for genomes, genes, gene expressions, gene variation, gene families, proteins, and protein domains are integrated with the analytical, search, and retrieval resources through the NCBI website, text-based search and retrieval system, provides a fast and easy way to navigate across diverse biological databases.

Comparative genome analysis tools lead to further understanding of evolution processes quickening the pace of discovery. Recent technological innovations have ignited an explosion in genome sequencing that has fundamentally changed our understanding of the biology of living organisms. This huge increase in DNA sequence data presents new challenges for the information management system and the visualization tools. New strategies have been designed to bring an order to this genome sequence shockwave and improve the usability of associated data.

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Acknowledgements

The authors would like to thank, in alphabetic order, Boris Fedorov and Sergei Resenchuk for their expertise and diligence in the design and maintenance of the databases highlighted in this publication and Stacy Ciufo for the helpful discussion and comments. These projects represent the efforts of many NCBI staff members along with the collective contributions of many dedicated scientists worldwide.

Author information

Authors and Affiliations

  1. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD, 20894, USA

    Tatiana Tatusova

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  1. Tatiana Tatusova
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Correspondence to Tatiana Tatusova .

Editor information

Editors and Affiliations

  1. Max F. Perutz Laboratories GmbH, Universität Wien, Wien, Austria

    Oliviero Carugo

  2. Technology and Research (A*STAR), Agency for Science, Singapore, Singapore

    Frank Eisenhaber

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Tatusova, T. (2016). Update on Genomic Databases and Resources at the National Center for Biotechnology Information. In: Carugo, O., Eisenhaber, F. (eds) Data Mining Techniques for the Life Sciences. Methods in Molecular Biology, vol 1415. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3572-7_1

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  • DOI: https://doi.org/10.1007/978-1-4939-3572-7_1

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3570-3

  • Online ISBN: 978-1-4939-3572-7

  • eBook Packages: Springer Protocols

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