Abstract
Pain assessment in animal models of osteoarthritis is integral to interpretation of a model’s utility in representing the clinical condition, and enabling accurate translational medicine. Here we describe two methods for behavioral pain assessments available for use in animal models of experimental osteoarthritic pain: Von Frey filaments and spontaneous activity monitoring.
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Acknowledgments
This work was supported by NIH NIAMS R01 grants to HJI from AR053220, AR062136 and VA BLD&R Merit Award.
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Piel, M.J., Kroin, J.S., Im, HJ. (2015). Assessment of Knee Joint Pain in Experimental Rodent Models of Osteoarthritis. In: Westendorf, J., van Wijnen, A. (eds) Osteoporosis and Osteoarthritis. Methods in Molecular Biology, vol 1226. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1619-1_13
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DOI: https://doi.org/10.1007/978-1-4939-1619-1_13
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Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-1618-4
Online ISBN: 978-1-4939-1619-1
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