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Ependymoma Models

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Animal Models of Brain Tumors

Part of the book series: Neuromethods ((NM,volume 77))

Abstract

Experimental neurocarcinogenesis using chemical agents or certain viruses can get brain tumors; some of them have been considered classically as ependymomas according to their histological aspects. However, it is now accepted that these tumors do not meet a clear criteria to be considered as ependymoma models. Xenografts of human ependymomas in nude mouse are most useful models, but they have the disadvantage that the absence of host immune response may mask important aspects currently considered in the biology of brain tumors.

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Author information

Authors and Affiliations

  1. Neurosurgical Department, Hospital Universitario Puerta de Hierro-Majadahonda, Autonomous University, Madrid, Spain

    Jesús Vaquero & Mercedes Zurita

Authors
  1. Jesús Vaquero
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  2. Mercedes Zurita
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Correspondence to Jesús Vaquero .

Editor information

Editors and Affiliations

  1. Instituto Cajal, Molecular, Cellular & Developmental Neur, CSIC, Avda. Doctor Arce 37, Madrid, 28002, Spain

    Ricardo Martínez Murillo

  2. de la Rioja (CIBIR), Oncology Area, Centro de Investigación Biomédica, C/ Piqueras 98, Logroño, 26006, Spain

    Alfredo Martínez

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Vaquero, J., Zurita, M. (2012). Ependymoma Models. In: Martínez Murillo, R., Martínez, A. (eds) Animal Models of Brain Tumors. Neuromethods, vol 77. Humana Press, Totowa, NJ. https://doi.org/10.1007/7657_2011_26

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  • DOI: https://doi.org/10.1007/7657_2011_26

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-208-7

  • Online ISBN: 978-1-62703-209-4

  • eBook Packages: Springer Protocols

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