Overview
- Presents a unique collection of the latest advances in identifying and understanding the role of non-coding RNA in sexual differentiation
- Covers both the role of non-coding RNAs in the development of the reproductive system and their implication in disease, such as breast and prostate cancer
- Comprehensive coverage of the function of non-coding RNAs in the development and disease of the reproductive system forms an invaluable basis for further functional studies
- Written by international experts in their field who provide the very latest details on non-coding RNA function
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 886)
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About this book
This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract.
The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.
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Table of contents (9 chapters)
Editors and Affiliations
Bibliographic Information
Book Title: Non-coding RNA and the Reproductive System
Editors: Dagmar Wilhelm, Pascal Bernard
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-94-017-7417-8
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 2016
Hardcover ISBN: 978-94-017-7415-4Published: 18 December 2015
Softcover ISBN: 978-94-024-1344-1Published: 30 March 2019
eBook ISBN: 978-94-017-7417-8Published: 11 December 2015
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VII, 198
Number of Illustrations: 26 b/w illustrations
Topics: Gene Function, Developmental Biology, Reproductive Medicine