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Stem Cell Therapy for Organ Failure

  • Book
  • © 2014

Overview

Editors:
  1. Indumathi Somasundaram

    1. Department of Stem Cells and Regenerative Medicine, Centre for Interdisciplinary Research, DY Patil University, Kolhapur, India

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  • A simple, reliable and unique book in the field of stem cell technology and regenerative medicine
  • Exclusively dedicated to the research and therapeutics of organ failure in different systems of human anatomy
  • A wide source of information for stem cell researchers, transplantation surgeons, scientists, medical practitioners & students

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xix
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  2. Stem Cells: Science/Concepts and Database

    1. Front Matter

      Pages 1-1
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    2. Promises of Stem Cell Research and Therapeutics

      • Indumathi Somasundaram, Kanmani Anandan, Dhanasekaran Marappagounder
      Pages 3-13

    3. Considerations for Culturing and Preserving Adult Stem Cells for Therapeutics

      • Simi M. Chacko, Periannan Kuppusamy
      Pages 15-30

    4. Bioinformatics Toolbox for Stem Cell Research and Therapeutics

      • Himadri Singh
      Pages 31-37

  3. Stem Cells and Organ Systems: Nervous System

    1. Front Matter

      Pages 39-39
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    2. Stem Cell Therapy for Neurological Disorders: From Bench to Bedside

      • Peter A. Barbuti
      Pages 41-70

    3. Stem Cells and Neuronal Differentiation

      • Indrani Datta, Debanjana Majumdar, Kavina Ganapathy, Ramesh R. Bhonde
      Pages 71-101

  4. Stem Cells and Organ Systems: Cardiovascular System

    1. Front Matter

      Pages 103-103
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    2. Stem Cell Therapy for Cardiac Tissue Regeneration Post-myocardial Infarction

      • Uksha Saini, Konstantinos Dean Boudoulas
      Pages 105-115

    3. Endothelial Progenitor Cells: Application in Vascular Medicine

      • Venkata Naga Srikanth Garikipati, Prasanna Krishnamurthy, Suresh Kumar Verma, Raj Kishore
      Pages 117-124

  5. Stem Cells and Organ Systems: Musculo Skeletal System

    1. Front Matter

      Pages 125-125
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    2. Bone Marrow Versus Dental Pulp Stem Cells in Osteogenesis

      • Mohammad Mahboob Kanafi, Sireesha Ganneru, Dhanasekaran Marappagounder, Padmanav Behera, Ramesh R. Bhonde
      Pages 127-141

    3. Adipose-Derived Stem Cells: In Musculoskeletal Disorders

      • Dhanasekaran Marappagounder, Sandeep Kumar Kotturu, Padmanav Behera, Rajanna Ajumeera, Ravikumar Rajappa
      Pages 143-149

  6. Stem Cells and Organ Systems: Hematopoietic System

    1. Front Matter

      Pages 151-151
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    2. Fetal Blood Research: A Brief Perspective on the Present, Past, and Future of This Exciting Field

      • Niranjan Bhattacharya, Sanjukta Bhattacharya
      Pages 153-156

    3. An Outline of Haematopoietic Stem Cell Transplantation

      • Revathy Raj
      Pages 157-165

    4. Placental Umbilical Cord Whole Blood and Nuclear Disaster Management: A Possibility

      • Niranjan Bhattacharya, Sanjukta Bhattacharya
      Pages 167-171

    5. Mesenchymal Stem Cell Treatment Option to Manage Autoimmune Disorders: A Technically Feasible Integration

      • Subadra Dravida, R. Indarapu
      Pages 173-177

  7. Stem Cells and Organ Systems: Gastrointestinal System

    1. Front Matter

      Pages 179-179
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Keywords

About this book

The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel the basic, advanced, therapeutic and translational approaches put-forth so far in the field of stem cells and regenerative medicine at research, pre-clinical and clinical levels. Stem cells has ushered in widespread interest and exciting possibilities for cell based therapies, albeit failures do prevail and small uncontrolled phase I/II studies are only signals generating, rather than definite proof of concept thereby limiting its applicability in curative therapeutics. Despite certain initiatives and meticulous untiring efforts, bringing this basic bench side research into advanced transitional bedside remained a challenge. Thus, this book embarked upon the expanding researches in these areas that seem decisive in improvising regenerative medical therapeutics, thereby leading to further path-breaking studies that cure all health challenges facing mankind. Overall, this book reveals the imperativeness of various stem cell sources and its utility in curative therapeutics.

Editors and Affiliations

  • Department of Stem Cells and Regenerative Medicine, Centre for Interdisciplinary Research, DY Patil University, Kolhapur, India

    Indumathi Somasundaram

About the editor

Dr. Indumathi Somasundaram is a Research Associate at Department of Stem cell, National Institute of Nutrition (ICMR), Secunderabad. She completed her master’s degree in 2008 from University of Madras (Loyola College, Chennai, India). After a brief work experience at Lifeline RIGID Hospitals as a Researcher for nearly 2 years, where she got introduced to stem cells, she proceeded to do PhD in stem cells, and awarded PhD from University of Madras in the year 2014. During her work and PhD, she gained research experience on different kinds of adult stem cells including bone marrow, adipose tissue and endometrium, its in-vitro attributes of self renewal and differentiation, and its therapeutic implications/applications. Her areas of interest and expertise include adult stem cells, regenerative biology, reproductive biology, diabetes, cancer stem cells and so on. She has more than 21 publications, of which 15 are indexed and 4 book chapters (Springer Verlag) to her credit and few more in pipeline. Her present interest and work lies on exploring the potentials of mesenchymal stem cells in treating diabetes and on identifying the possible causes and cues of endometrial disorders and its management. Besides, she is exploring microRNA regulatory mechanisms in physiology and pathology of diseases.

Bibliographic Information

  • Book Title: Stem Cell Therapy for Organ Failure

  • Editors: Indumathi Somasundaram

  • DOI: https://doi.org/10.1007/978-81-322-2110-4

  • Publisher: Springer New Delhi

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer India 2014

  • Hardcover ISBN: 978-81-322-2109-8Published: 21 January 2015

  • Softcover ISBN: 978-81-322-3487-6Published: 06 October 2016

  • eBook ISBN: 978-81-322-2110-4Published: 02 January 2015

  • Edition Number: 1

  • Number of Pages: XIX, 278

  • Number of Illustrations: 9 b/w illustrations, 34 illustrations in colour

  • Topics: Biomedicine general, Cell Biology, Stem Cells

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