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New Mechanisms for Tissue-Selective Estrogen-Free Contraception

  • Conference proceedings
  • © 2005

Overview

Editors:
  1. H. B. Croxatto

    1. Instituto Chileno de Medicina Reproductive (ICMER), Santiago de Chile, Chile

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  2. R. Schürmann

    1. Strategic Business Unit, Gynecology and Andrology, Schering AG, Berlin, Germany

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  3. U. Fuhrmann

    1. CRBA, Gynecology and Andrology, Female Health Care, Schering AG, Berlin, Germany

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  4. I. Schellschmidt

    1. Strategic Business Unit, Gynecology and Andrology, Schering AG, Berlin, Germany

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Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 52)

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Table of contents (11 papers)

  1. Front Matter

    Pages I-XII
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  2. Progesterone Receptors and Opportunities for Contraception

    • H. B. Croxatto
    Pages 1-17

  3. Reproductive Tissue-Selective Actions of Progesterone Receptors

    • B. Mulac-Jericevic, O. M. Conneely
    Pages 19-37

  4. The Progesterone Receptor/Estradiol Receptor Association and the Progestin-Triggered S-Phase Entry

    • A. Migliaccio, G. Castoria, M. Di Domenico, C. Ballaré, M. Beato, F. Auricchio
    Pages 39-54

  5. Endometrial Morphology and Progestogens

    • H. O. D. Critchley
    Pages 55-88

  6. Role of Progesterone in the Structural and Biochemical Remodeling of the Primate Endometrium

    • O. D. Slayden, R. M. Brenner
    Pages 89-118

  7. Effects of Progestogens on Endometrial Maturation in the Implantation Phase

    • K. Gemzell-Danielsson, M. Bygdeman
    Pages 119-138

  8. Gene Expression During the Implantation Window: Microarray Analysis of Human Endometrial Samples

    • A. Schmidt, P. Groth, B. Haendler, H. Hess-Stumpp, J. Krätzschmar, H. Seidel et al.
    Pages 139-157

  9. Role of EBAF/Lefty in Implantation and Uterine Bleeding

    • S. Tabibzadeh
    Pages 159-189

  10. Mechanisms Underlying Menstrual Bleeding Disturbances with Progestogens

    • M. Hickey, C. d’Arcangues
    Pages 191-217

  11. Human Endocervical Mucins

    • I. K. Gipson
    Pages 219-244

  12. Fallopian Tube Physiology: Preliminaries to Monospermic Fertilization and Cellular Events Post-fertilization

    • R. H. F. Hunter
    Pages 245-261

  13. Back Matter

    Pages 263-266
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Keywords

About this book

Combined oral contraceptives are the most convenient and accepted method of hormonal contraception. Nevertheless, the medical community and consumers constantly demand innovation, additional benefits during use and lower hormonal load despite the high safety profile of available products. At the Ernst Schering Research Foundation Workshop 52, new perspectives and mechanisms for tissue-selective, estrogen-free contraception were discussed. The aim of the workshop was to bring together experts in the field of molecular and pharmacodynamic action of progestins with clinicians and medical experts to discuss potential medical endpoints, physiological reactions and (bio)marker useful describing the tissue selectivity and the contraceptive action of new progestins in different target organs. A major factor for successful realization of these new concepts is a deeper understanding of local pharmacological responses to progestins in general and to new progestins in particular.

Editors and Affiliations

  • Instituto Chileno de Medicina Reproductive (ICMER), Santiago de Chile, Chile

    H. B. Croxatto

  • Strategic Business Unit, Gynecology and Andrology, Schering AG, Berlin, Germany

    R. Schürmann, I. Schellschmidt

  • CRBA, Gynecology and Andrology, Female Health Care, Schering AG, Berlin, Germany

    U. Fuhrmann

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