Skip to main content
Log in

Liver Transection-First Approach in Left Trisectionectomy for Perihilar Cholangiocarcinoma

  • Hepatobiliary Tumors
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Left trisectionectomy [(LT) resection of segments 2, 3, 4, 5, 8, and 1] for perihilar cholangiocarcinoma is still a challenging procedure with high postoperative morbidity and mortality. To perform LT safely, the liver transection-first approach was developed. In this approach, liver transection is started without dividing the right anterior hepatic artery (RAHA) and right anterior portal vein (RAPV). After the completion of liver transection, the RAHA and RAPV, which run into the future resected liver, can be easily identified and divided under the wide surgical field at the hepatic hilus. The liver transection-first approach appears to be safer than the conventional LT, leading to less postoperative morbidity and mortality.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Miyazaki M, Kato A, Ito H, et al. Combined vascular resection in operative resection for hilar cholangiocarcinoma: does it work or not? Surgery. 2007;141:581–8.

    Article  Google Scholar 

  2. Miyazaki M, Kimura F, Shimizu H, et al. One hundred seven consecutive surgical resections for hilar cholangiocarcinoma of Bismuth types II, III, IV between 2001 and 2008. J Hepatobiliary Pancreat Sci. 2010;17:470–5.

    Article  Google Scholar 

  3. Shimizu H, Kimura F, Yoshidome H, et al. Aggressive surgical resection for hilar cholangiocarcinoma of the left-side predominance. Ann Surg. 2010;251:281–6.

    Article  Google Scholar 

  4. Hosokawa I, Shimizu H, Yoshidome H, et al. Surgical strategy for hilar cholangiocarcinoma of the left-side predominance: current role of left trisectionectomy. Ann Surg. 2014;259:1178–85.

    Article  Google Scholar 

  5. Hosokawa I, Shimizu H, Yoshitomi H, et al. Impact of biliary drainage on multidetector-row computed tomography on R0 resection of perihilar cholangiocarcinoma. World J Surg. 2018;42:3676–84.

    Article  Google Scholar 

  6. Nagino M, Ebata T, Yokoyama Y, et al. Evolution of surgical treatment for perihilar cholangiocarcinoma: a single-center 34-year review of 574 consecutive resections. Ann Surg. 2013;258:129–40.

    Article  Google Scholar 

  7. Miyazaki M, Yoshitomi H, Miyakawa S, et al. Clinical practice guidelines for the management of biliary tract cancers 2015: the 2nd English edition. J Hepatobiliary Pancreat Sci. 2015;22:249–73.

  8. Hosokawa I, Shimizu H, Yoshitomi H, et al. Outcomes of left trisectionectomy ant right hepatectomy for perihilar cholangiocarcinoma. HPB. 2019;21:489–98.

    Article  Google Scholar 

  9. Hosokawa I, Ohtsuka M, Yoshitomi H, et al. Right intersectional transection plane based on portal inflow in left trisectionectomy. Surg Radiol Anat. 2019;41:589–93.

    Article  Google Scholar 

  10. Shimizu H, Sawada S, Kimura F, et al. Clinical significance of biliary vascular anatomy of the right liver for hilar cholangiocarcinoma applied to left hemihepatectomy. Ann Surg. 2009;49:435–9.

    Article  Google Scholar 

  11. Yoshioka Y, Ebata T, Yokoyama Y, et al. Supraportal right posterior hepatic artery: an anatomic trap in hepatobiliary and transplant surgery. World J Surg. 2011;35:1340–4.

    Article  Google Scholar 

  12. Lee MK, Gao F, Strasberg SM. Perceived complexity of various liver resections: results of 30 a survey of experts with development of a complexity score and classification. J Am Coll Surg. 2015;220:64–9.

    Article  Google Scholar 

  13. Otsubo T, Kobayashi S, Sano K, et al. Safety-related outcomes of the Japanese Society of Hepato-Biliary-Pancreatic Surgery board certification system for expert surgeons. J Hepatobiliary Pancreat Sci. 2017;24:252–61.

    Article  Google Scholar 

  14. Shimizu H, Hosokawa I, Ohtsuka M, et al. Clinical significance of anatomical variant of the left hepatic artery for perihilar cholangiocarcinoma applied to right-sided hepatectomy. World J Surg. 2014;38:3210–4.

    Article  Google Scholar 

  15. Kuriyama N, Isaji S, Tanemura A, et al. Transhepatic hilar approach for perihilar cholangiocarcinoma: significance of early judgment of resectability and safe vascular reconstruction. J Gastrointest Surg. 2017;21:590–9.

    Article  Google Scholar 

  16. Natsume S, Ebata T, Yokoyama Y, et al. Clinical significance of left trisectionectomy for perihilar cholangiocarcinoma: an appraisal and comparison with left hepatectomy. Ann Surg. 2012;255:754–62.

    Article  Google Scholar 

  17. Nagino M, Kamiya J, Nishio H, et al. Two hundred forty consecutive portal vein embolizations before extended hepatectomy for biliary cancer: surgical outcome and long-term follow-up. Ann Surg. 2006;243:364–72.

    Article  Google Scholar 

  18. Ebata T, Yokoyama Y, Igami T, et al. Portal vein embolization before extended hepatectomy for biliary cancer: current technique and review of 494 consecutive embolizations. Dig Surg. 2012;29:23–9.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hiroaki Shimizu MD, PhD.

Ethics declarations

DISCLOSURE

The authors declare that they have no conflicts of interest and received no funding support for this research.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic supplementary material

Below is the link to the electronic supplementary material.

10434_2020_8306_MOESM1_ESM.pptx

The three-dimensional positional relationship of the right anterior hepatic artery or the right posterior hepatic artery to the right portal vein (A), and the three-dimensional positional relationship of the right anterior sectional bile duct or the right posterior sectional bile duct to the right portal vein (B). RAHA, right anterior hepatic artery; RPHA, right posterior hepatic artery; A6, hepatic artery of segment 6; A7, hepatic artery of segment 7; PV, portal vein; BD, bile duct; RASBD, right anterior sectional bile duct; RPSBD, right posterior sectional bile duct; B6, bile duct of segment 6; B7, bile duct of segment 7 (PPTX 1315 kb)

Surgical video of the left trisectionectomy (resection of segments 2, 3, 4, 5, 8, and 1) with extrahepatic bile duct resection using the liver transection-first approach (MP4 142673 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hosokawa, I., Shimizu, H., Ohtsuka, M. et al. Liver Transection-First Approach in Left Trisectionectomy for Perihilar Cholangiocarcinoma. Ann Surg Oncol 27, 2381–2386 (2020). https://doi.org/10.1245/s10434-020-08306-y

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1245/s10434-020-08306-y

Navigation