Abstract
The complexity of even the simplest of life forms, the single cell, cannot be overstated. Nevertheless, from a chemical perspective, cellular components can be segregated into macromolecules (DNA, RNA, proteins, etc.), relatively simple molecules (amino acids, monosaccharides, and lipids), and their precursors: CO2, H2O, and NH3. In general, the macromolecules tend to be polymers of small biomolecules; however, each of these molecules, whether simple or complex, is involved in a myriad of intricate metabolic reactions. A case in point is the monosaccharide glucose which is synthesized from H2O and CO2. When degraded to its precursors, it provides the cell with its energy requirements for such diverse processes as macroscopic movement as well as the synthesis of complex macromolecules. In addition, glucose is the fundamental building block of macromolecules such as starch and cellulose. This basic theme, in which the cell uses a simple small molecule in a multitude of processes, is typical of how relatively small biomolecules are used in living systems.
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Reference
Van’t Hoff JH (1875) La chimie dan l’espace, P.M. Bazendijk, Rotterdam
Further Readings
Hudson CS (1941) Emil Fischer’s discovery of the configuration of glucose. A semicentennial retrospect. J Chem Edu 18:353–357
Hudson CS (1953) The basic work of Fischer and Van’t Hoff in carbohydrate chemistry. J Chem Educ 30:120–121
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© 2012 Springer-Verlag Berlin Heidelberg
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Fromm, H.J., Hargrove, M.S. (2012). Introduction to Biomolecules. In: Essentials of Biochemistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19624-9_2
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DOI: https://doi.org/10.1007/978-3-642-19624-9_2
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-19623-2
Online ISBN: 978-3-642-19624-9
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