Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors T. S. GarimellaD. D. RossK. S. Bauer Original Article 01 October 2004 Pages: 101 - 109
P-glycoprotein plays a role in the oral absorption of BMS-387032, a potent cyclin-dependent kinase 2 inhibitor, in rats Amrita V. KamathSaeho ChongPunit H. Marathe Original Article 27 August 2004 Pages: 110 - 116
Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours P. M. J. McSheehyR. E. PortJ. R. Griffiths Original Article 05 October 2004 Pages: 117 - 128
Lack of strain-related differences in drug metabolism and efflux transporter characteristics between CD-1 and athymic nude mice Marcella MartignoniRuben de KanterMario Monshouwer Original Article 22 September 2004 Pages: 129 - 135
A phase I and pharmacologic study of the matrix metalloproteinase inhibitor CP-471,358 in patients with advanced solid tumors André PlantingAte van der GaastJaap Verweij Original Article 29 September 2004 Pages: 136 - 142
Comparative preclinical toxicology and pharmacology of isophosphoramide mustard, the active metabolite of ifosfamide N. GermannS. UrienLee Roy Morgan Original Article 14 September 2004 Pages: 143 - 151
Alternating weekly administration of paclitaxel and gemcitabine: a phase II study in patients with advanced non-small-cell lung cancer David AguiarJosé AguiarUriel Bohn Original Article 22 September 2004 Pages: 152 - 158
Absorption and metabolism of genistein and its five isoflavone analogs in the human intestinal Caco-2 model Jun ChenHuimin LinMing Hu Original Article 29 September 2004 Pages: 159 - 169
Tissue distribution of arsenic species in rabbits after single and multiple parenteral administration of arsenic trioxide: tissue accumulation and the reversibility after washout are tissue-selective Chun-Jung LinMei-Hwan WuAnn-Lii Cheng Original Article 21 August 2004 Pages: 170 - 178
Reversal of multidrug resistance of cancer through inhibition of P-glycoprotein by 5-bromotetrandrine Jing JinFeng-Peng WangGengtao Liu Original Article 16 September 2004 Pages: 179 - 188
Synergistic antitumor activity of TRAIL combined with chemotherapeutic agents in A549 cell lines in vitro and in vivo Qing-Lin FanWen-Yi ZouWei Wei Original Article 29 July 2004 Pages: 189 - 196
Phase II study of a fixed dose-rate infusion of gemcitabine associated with docetaxel in advanced non-small-cell lung carcinoma J. De CastroA. LorenzoOncopaz Cooperative Group Original Article 21 August 2004 Pages: 197 - 202