A phase I/II study of continuous infusion suramin in patients with hormone-refractory prostate cancer : toxicity and response C. J. BowdenW. D. FiggM. R. Cooper ORIGINAL ARTICLE Pages: 1 - 8
The effects of food and divided dosing on the bioavailability of oral vinorelbine E. K. RowinskyV. Sol LucasRoss C. Donehower ORIGINAL ARTICLE Pages: 9 - 16
Intraliposomal conversion of lipophilic cis-bis-carboxylato-trans-R, R-1, 2-diaminocyclohexane-platinum (II) complexes into cis-bis-dichloro-trans-R, R-1,2-diaminocyclohexane-platinum (II) Han. InsookAbdul R. KhokharR. Perez-Soler ORIGINAL ARTICLE Pages: 17 - 24
Cisplatin pharmacokinetics and pharmacodynamics in patients with squamous-cell carcinoma of the head/neck or esophagus A. JohnssonPeter HöglundEva Cavallin-Sta˚hl ORIGINAL ARTICLE Pages: 25 - 33
Pharmacokinetic studies of 13-cis-retinoic acid in pediatric patients with neuroblastoma following bone marrow transplantation A. A. KhanJudith G. VillablancaVassilios I. Avramis ORIGINAL ARTICLE Pages: 34 - 41
NONMEM population pharmacokinetic studies of cytosine arabinoside after high-dose and after loading bolus followed by continuous infusion of the drug in pediatric patients with leukemias Antonia P. PericlouV. I. Avramis ORIGINAL ARTICLE Pages: 42 - 50
Plasma pharmacokinetics, bioavailability, and tissue distribution in CD2F1 mice of halomon, an antitumor halogenated monoterpene isolated from the red algae Portieria hornemannii M. J. EgorinDorothy L. SentzJulie L. Eiseman ORIGINAL ARTICLE Pages: 51 - 60
Pharmacodynamic modeling of prolonged administration of etoposide H. MinamiMark J. RatainK. Shimokata ORIGINAL ARTICLE Pages: 61 - 66
Electropermeabilization in bladder cancer chemotherapy Y. KubotaTeruhiro NakadaMorihiro Watanabe ORIGINAL ARTICLE Pages: 67 - 70
In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts Øystein Bruserud ORIGINAL ARTICLE Pages: 71 - 78
Tumor size and origin determine the antitumor activity of cisplatin or 5-fluorouracil and its modulation by leucovorin in murine colon carcinomas J. A. M. Van LaarYoucef M. RustumJ. A. M. Van Laar ORIGINAL ARTICLE Pages: 79 - 89
Interstitial delivery of carboplatin via biodegradable Polymers is effective against experimental glioma in the rat A. OliviMatthew G. EwendHenry Brem ORIGINAL ARTICLE Pages: 90 - 96
The human cell multiprotein DNA replication complex (MRC): the effect of camptothecin on its ability to support in vitro DNA synthesis Jennifer M. CollRobert J. HickeyL. H. Malkas ORIGINAL ARTICLE Pages: 97 - 102
Lyophilized preliposomal formulation of the non-cross-resistant anthracycline annamycin: effect of surfactant on liposome formation, stability and size Y. ZouWaldemar PriebeRoman Perez-Soler ORIGINAL ARTICLE Pages: 103 - 108
The significance of the sequence of administration of topotecan and etoposide J. A. BonnerTimothy F. Kozelsky ORIGINAL ARTICLE Pages: 109 - 112
Effect of angiotensin II on immunotoxin uptake in tumor and normal tissue Felipe G. Elizondo Jr.Cynthia Sung ORIGINAL ARTICLE Pages: 113 - 121
Influence of route of administration on [3H]-camptothecin distribution and tumor uptake in CASE-bearing nude mice: whole-body autoradiographic studies A. E. AhmedSam JacobJoachim G. Liehr ORIGINAL ARTICLE Pages: 122 - 130
Relationship between pharmacokinetics of unchanged cisplatin and nephrotoxicity after intravenous infusions of cisplatin to cancer patients Naomi NagaiMasafumi KinoshitaYuzou Kurita ORIGINAL ARTICLE Pages: 131 - 137
The effect of vincristine–polyanion complexes in STEALTH liposomes on pharmacokinetics, toxicity and anti tumor activity George ZhuEdwin OtoG. Zhu ORIGINAL ARTICLE Pages: 138 - 142
Myelotoxic effects of the bifunctional alkylating agent bizelesin on human, canine and murine myeloid progenitor cells D. A. VolpeJoseph E. TomaszewskiCharles K. Grieshaber ORIGINAL ARTICLE Pages: 143 - 149
Vinorelbine-induced neurotoxicity in patients with advanced breast cancer pretreated with paclitaxel – a phase II study B. FazenyU. ZifkoChristian Dittrich CLINICAL TRIAL REPORT Pages: 150 - 156
Comparative activity of idarubicin and idarubicinol in combination with cyclosporin A in multidrug-resistant leukemia cells M. TolomeoRosa Alba GancitanoAurelio Cajozzo SHORT COMMUNICATION Pages: 157 - 161
Pharmacokinetics of amifostine and its metabolites in the plasma and ascites of a cancer patient A. E. C. KorstHelen E. GallWim J. F. van der Vijgh SHORT COMMUNICATION Pages: 162 - 166
Photodynamic damage to HeLa cell microtubules induced by thiazine dyes J. C. StockertAngeles JuarranzMagdalena Cañete SHORT COMMUNICATION Pages: 167 - 169
The tissue distribution in BALB/c mice of C-14-labeled JM216, an orally active platinum antitumour compound P. I. BatesH. L. SharmaC. A. McAuliffe SHORT COMMUNICATION Pages: 170 - 175
Vinca alkaloids and macrolides in human immunodeficiency virus-related malignancies: a safe association A. TorresinGiovanni CassolaNicolò Piersantelli LETTER TO THE EDITORS Pages: 176 - 177