1. Tumor apoptosis induced by epoxide-containing piperazines, a new class of anti-cancer agents

   • Gabriel F. Eilon
   • Jirong Gu
   • John W. Jacobs

   ORIGINAL ARTICLE Pages: 183 - 191

2. Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice

   • Nil Dizdar
   • Anita Kullman
   • Bertil Kågedal

   ORIGINAL ARTICLE Pages: 192 - 198

3. Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma

   • Kazutake Seki
   • Hideshi Yoshikawa
   • Kachio Tasaka

   ORIGINAL ARTICLE Pages: 199 - 206

4. Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates

   • Katherine E. Warren
   • Mahendra C. Patel
   • Frank M. Balis

   ORIGINAL ARTICLE Pages: 207 - 212

5. Pharmacokinetics and metabolism of docetaxel administered as a 1-h intravenous infusion

   • H. Rosing
   • V. Lustig
   • J. H. Beijnen

   ORIGINAL ARTICLE Pages: 213 - 218

6. Modulation of Adriamycin cytotoxicity and transport in drug-sensitive and multidrug-resistant Chinese hamster ovary cells by hyperthermia and cyclosporin A

   • Bruno Larrivée
   • Diana A. Averill

   ORIGINAL ARTICLE Pages: 219 - 230

7. Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts

   • Patrick W. Vincent
   • Alex J. Bridges
   • William L. Elliott

   ORIGINAL ARTICLE Pages: 231 - 238

8. Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer – effect of sequence

   • Emil Frei III
   • Gulshan Ara
   • Anthony Elias

   ORIGINAL ARTICLE Pages: 239 - 246

9. Pharmacokinetics of levamisole in cancer patients treated with 5-fluorouracil

   • Peter Gwilt
   • Margaret Tempero
   • Cliff Ding

   ORIGINAL ARTICLE Pages: 247 - 251

10. Enhancement of camptothecin-induced cytotoxicity with UCN-01 in breast cancer cells: abrogation of S/G₂ arrest

    • Carleton B. Jones
    • Mark K. Clements
    • Sayed S. Daoud

    ORIGINAL ARTICLE Pages: 252 - 258

11. Methotrexate distribution within the subarachnoid space after intraventricular and intravenous administration

    • Frank M. Balis
    • Susan M. Blaney
    • John D. Bacher

    ORIGINAL ARTICLE Pages: 259 - 264