1. Clinical pharmacology and primary health care in Europe — a gap to bridge

   • G. Dukes
   • P. K. M. Lunde
   • The WHO Working Group on Clinical Pharmacology in Europe

   Special Article Pages: 315 - 318

2. Informed consent in clinical research with drugs in Spain: Perspective of clinical trials committee members

   • R. Dal-Ré

   Originals Pages: 319 - 324

3. Drug use in pregnancy: an overview of epidemiological (drug utilization) studies

   • M. Bonati
   • R. Bortolus
   • G. Tognoni

   Originals Pages: 325 - 328

4. Prescription monitoring of drug dosages in the county of Jämtland and Sweden as a whole in 1976, 1982 and 1985

   • A. Wessling
   • G. Boëthius
   • F. Sjöqvist

   Originals Pages: 329 - 334

5. Digoxin infusion versus bolus injection in rapid atrial fibrillation: relation between serum level and response

   • A. J. Smit
   • A. H. J. Scaf
   • H. Wesseling

   Originals Pages: 335 - 341

6. Plasma and cerebrospinal fluid concentrations of indomethacin in humans

   • B. Bannwarth
   • P. Netter
   • A. Gaucher

   Originals Pages: 343 - 346

7. Effects of taprostene, a stable prostacyclin analogue, on haemodynamics, platelet function and arachidonate metabolism in healthy volunteers

   • I. Virgolini
   • P. Fitscha
   • H. Barth

   Originals Pages: 347 - 350

8. A comparison of the haemodynamic and hormonal effects of low and conventional dose cyclopenthiazide in normal volunteers

   • G. E. McVeigh
   • M. McMaster
   • G. D. Johnston

   Originals Pages: 351 - 357

9. Effect of diuretics on captopril-induced urinary zinc excretion

   • A. Golik
   • Z. Averbukh
   • D. Modai

   Originals Pages: 359 - 361

10. Beta-adrenoceptor blockade potentiates exercise-induced release of atrial natriuretic peptide

    • G. Deray
    • I. Berlin
    • C. Jacobs

    Originals Pages: 363 - 366

11. Effect of loxiglumide (CR-1505) on bombesin- and meal-stimulated plasma cholecystokinin in man

    • J. B. M. J. Jansen
    • M. C. W. Jebbink
    • C. B. H. W. Lamers

    Originals Pages: 367 - 370

12. Effects of adinazolam and diazepam, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers

    • M. Linnoila
    • J. M. Stapleon
    • M. J. Eckardt

    Originals Pages: 371 - 377

13. Pharmacokinetics and pharmacodynamics of the ace inhibitor benazepril hydrochloride in the elderly

    • G. Kaiser
    • R. Ackermann
    • I. B. Holmes

    Originals Pages: 379 - 385

14. Agranulocytosis induced by cinepazide

    • J. -R. Laporte
    • D. Capellà
    • J. Juan

    Short Communications Pages: 387 - 388

15. Anaphylactic shock induced by paracetamol

    • Le Van Diem
    • J. P. Grilliat

    Short Communications Pages: 389 - 390

16. Circulating met-enkephalin in trained athletes during rest, exhaustive treadmill exercise and marathon running

    • K. De Sommers
    • J. M. Loots
    • J. le R. Human

    Short Communications Pages: 391 - 392

17. Insulin-induced increase in heart rate and its prevention by propranolol

    • A. Siani
    • P. Strazzullo
    • M. Mancini

    Short Communications Pages: 393 - 395

18. Effect of amiodarone on ³H-ouabain binding sites in human skeletal muscle

    • A. Nørgaard
    • J. H. Jensen
    • F. Andreasen

    Short Communications Pages: 397 - 399

19. The effect of neostigmine on metoclopramide-induced aldosterone secretion after the administration of muscarinic antagonists in man

    • K. De Sommers
    • E. C. Meyer
    • M. van Wyk

    Short Communications Pages: 401 - 403

20. Oral pharmacokinetics of pirenzepine in patients with chronic renal insufficiency, failure, and maintenance haemodialysis

    • T. MacGregor
    • K. Matzek
    • A. Chonko

    Short Communications Pages: 405 - 406

21. Drug treatment in hypertension — metabolic side effects of drugs

    • P. Little
    • A. Trafford
    • A. Craven

    Letter To The Editors Pages: 407 - 408

22. Announcements

    Announcement Pages: 408 - 408