1. Clinical and statistical issues in therapeutic equivalence trials

   • E. Garbe
   • J. Röhmel
   • U. Gundert-Remy

   Opinion Paper Pages: 1 - 7

2. Drug use in pregnancy: A comparative appraisal of data collecting methods

   • L. T. W. de Jong-van den Berg
   • C. M. Waardenburg
   • H. Wesseling

   Originals Pages: 9 - 14

3. Motives and perception of healthy volunteers who participate in experiments

   • C. E. M. van Gelderen
   • T. J. F. Savelkoul
   • J. Meulenbelt

   Originals Pages: 15 - 19

4. Effect of chronic treatment with enalapril on glucose tolerance and serum insulin in non-insulin-resistant Japanese patients with essential hypertension

   • T. Baba
   • T. Kodama
   • T. Ishizaki

   Originals Pages: 23 - 27

5. Effect of pinacidil on renal haemodynamics, tubular function and plasma levels of angiotensin II, aldosterone and atrial natriuretic peptide in healthy man

   • C. Brøckner Nielsen
   • E. Bjerregaard Pedersen

   Originals Pages: 29 - 35

6. The extrapulmonary effects of inhaled hexoprenaline and salbutamol in healthy individuals

   • P. Bremner
   • C. Burgess
   • J. Crane

   Originals Pages: 37 - 39

7. Effect of concomitant administration of cimetidine and ranitidine on the pharmacokinetics and electrocardiographic effects of terfenadine

   • P. K. Honig
   • D. C. Wortham
   • L. R. Cantilena

   Originals Pages: 41 - 46

8. Factors related to QT interval prolongation during probucol treatment

   • Y. Ohya
   • K. Kumamoto
   • M. Fujishima

   Originals Pages: 47 - 52

9. The effect of nitric oxide-donating vasodilators on monocyte chemotaxis and intracellular cGMP concentrations in vitro

   • P. M. W. Bath

   Originals Pages: 53 - 58

10. The disposition and protein binding of batanopride and its metabolites in subjects with renal impairment

    • J. V.St. Peter
    • M. E. Brady
    • C. E. Halstenson

    Originals Pages: 59 - 63

11. Similar effect of oxidation deficiency (debrisoquine polymorphism) and quinidine on the apparent volume of distribution of (±)-metoprolol

    • T. D. Leemann
    • K. P. Devi
    • P. Dayer

    Originals Pages: 65 - 71

12. Pharmacokinetic study and effects on growth hormone secretion in healthy volunteers of the new somatostatin analogue BIM 23014

    • J. M. Kuhn
    • C. Basin
    • G. Tolis

    Originals Pages: 73 - 77

13. Pharmacokinetics of oral tiopronin

    • M. S. Carlsson
    • T. Denneberg
    • S. Lindgren

    Originals Pages: 79 - 84

14. Relaxant effects of mefloquine on vascular smooth muscle in vitro

    • B. J. Adegunloye
    • O. A. Sofola
    • H. A. B. Coker

    Short Communications Pages: 85 - 88

15. Pharmacokinetics of diphemanil methylsulphate in infants

    • A. M. Vidal
    • G. Chéron
    • G. Olive

    Short Communications Pages: 89 - 91

16. Announcements

    Announcement Pages: 92 - 92