Volume 10, issue 1, December 2017
175 articles in this issue
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Recent development in clinical applications of PD-1 and PD-L1 antibodies for cancer immunotherapy
Authors
- Bingshan Liu
- Yongping Song
- Delong Liu
- Content type: Review
- Open Access
- Published: 01 December 2017
- Article: 174
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Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets
Authors (first, second and last of 10)
- Deepika Kanojia
- Manoj Garg
- H. Phillip Koeffler
- Content type: Research
- Open Access
- Published: 13 November 2017
- Article: 173
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AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways
Authors (first, second and last of 5)
- Yi-Hua Lai
- Sih-Yin Lin
- Jeremy J. W. Chen
- Content type: Research
- Open Access
- Published: 13 November 2017
- Article: 172
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Observational study of lenalidomide in patients with mantle cell lymphoma who relapsed/progressed after or were refractory/intolerant to ibrutinib (MCL-004)
Authors (first, second and last of 12)
- Michael Wang
- Stephen J. Schuster
- Peter Martin
- Content type: Research
- Open Access
- Published: 02 November 2017
- Article: 171
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Role of AP-2α and MAPK7 in the regulation of autocrine TGF-β/miR-200b signals to maintain epithelial-mesenchymal transition in cholangiocarcinoma
Authors (first, second and last of 7)
- Dawei Zhang
- Haiyan Li
- Ping Xue
- Content type: Research
- Open Access
- Published: 30 October 2017
- Article: 170
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Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis
Authors (first, second and last of 5)
- Jahangir Abdi
- Nasrin Rastgoo
- Hong Chang
- Content type: Review
- Open Access
- Published: 26 October 2017
- Article: 169
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A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors
Authors (first, second and last of 23)
- Luqiao Wang
- Gayani Nanayakkara
- Xiaofeng Yang
- Content type: Research
- Open Access
- Published: 24 October 2017
- Article: 168
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The emerging roles of NGS-based liquid biopsy in non-small cell lung cancer
Authors
- Yi-Chen Zhang
- Qing Zhou
- Yi-Long Wu
- Content type: Review
- Open Access
- Published: 23 October 2017
- Article: 167
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Clinical trials of CAR-T cells in China
Authors
- Bingshan Liu
- Yongping Song
- Delong Liu
- Content type: Rapid communication
- Open Access
- Published: 23 October 2017
- Article: 166
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The crosstalk between autophagic and endo-/exosomal pathways in antigen processing for MHC presentation in anticancer T cell immune responses
Authors (first, second and last of 8)
- Liangshun You
- Liping Mao
- Wenbin Qian
- Content type: Review
- Open Access
- Published: 23 October 2017
- Article: 165
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The role of B cell antigen receptors in mantle cell lymphoma
Authors (first, second and last of 4)
- Michael Fichtner
- Martin Dreyling
- Martin Trepel
- Content type: Review
- Open Access
- Published: 17 October 2017
- Article: 164
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Erratum to: MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis
Authors (first, second and last of 12)
- Yingmei Wang
- Limei Hu
- Wei Zhang
- Content type: Erratum
- Open Access
- Published: 06 October 2017
- Article: 163
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An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia
Authors (first, second and last of 12)
- Zhisheng Her
- Kylie Su Mei Yong
- Qingfeng Chen
- Content type: Research
- Open Access
- Published: 06 October 2017
- Article: 162
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Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells
Authors (first, second and last of 21)
- Francesca Megiorni
- Giovanni Luca Gravina
- Francesco Marampon
- Content type: Research
- Open Access
- Published: 06 October 2017
- Article: 161
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Erratum to: Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test
Authors (first, second and last of 10)
- Eddy C. Hsueh
- James R. DeBloom
- Kelly M. McMasters
- Content type: Erratum
- Open Access
- Published: 05 October 2017
- Article: 160
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The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis
Authors (first, second and last of 13)
- Lina Yang
- Li Liu
- Jianchang Yang
- Content type: Research
- Open Access
- Published: 03 October 2017
- Article: 159
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Association of a novel point mutation in MSH2 gene with familial multiple primary cancers
Authors (first, second and last of 8)
- Hai Hu
- Hong Li
- Liwei Wang
- Content type: Research
- Open Access
- Published: 03 October 2017
- Article: 158
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Role of protein kinases CK1α and CK2 in multiple myeloma: regulation of pivotal survival and stress-managing pathways
Authors
- Sabrina Manni
- Marilena Carrino
- Francesco Piazza
- Content type: Review
- Open Access
- Published: 02 October 2017
- Article: 157
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Long-term survival in patients treated with ruxolitinib for myelofibrosis: COMFORT-I and -II pooled analyses
Authors (first, second and last of 14)
- Srdan Verstovsek
- Jason Gotlib
- Vikas Gupta
- Content type: Research
- Open Access
- Published: 29 September 2017
- Article: 156
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Recent advances of bispecific antibodies in solid tumors
Authors (first, second and last of 9)
- Shengnan Yu
- Anping Li
- Kongming Wu
- Content type: Review
- Open Access
- Published: 20 September 2017
- Article: 155
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Erratum to: Romidepsin for the treatment of relapsed/refractory peripheral T cell lymphoma: prolonged stable disease provides clinical benefits for patients in the pivotal trial
Authors (first, second and last of 8)
- Francine Foss
- Steven Horwitz
- Bertrand Coiffier
- Content type: Erratum
- Open Access
- Published: 18 September 2017
- Article: 154
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Early presence of anti-angiogenesis-related adverse events as a potential biomarker of antitumor efficacy in metastatic gastric cancer patients treated with apatinib: a cohort study
Authors (first, second and last of 18)
- Xinyang Liu
- Shukui Qin
- Jin Li
- Content type: Short report
- Open Access
- Published: 05 September 2017
- Article: 153
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Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test
Authors (first, second and last of 10)
- Eddy C. Hsueh
- James R. DeBloom
- Kelly M. McMasters
- Content type: Research
- Open Access
- Published: 29 August 2017
- Article: 152
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Chimeric antigen receptors for adoptive T cell therapy in acute myeloid leukemia
Authors (first, second and last of 8)
- Mingxue Fan
- Minghao Li
- Lei Yu
- Content type: Review
- Open Access
- Published: 29 August 2017
- Article: 151
This is part of 1 collection: -
Novel immunotherapies for adult patients with B-lineage acute lymphoblastic leukemia
Authors (first, second and last of 4)
- Guoqing Wei
- Jiasheng Wang
- Yanmin Zhao
- Content type: Review
- Open Access
- Published: 18 August 2017
- Article: 150
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Treatment of localized gastric and gastroesophageal adenocarcinoma: the role of accurate staging and preoperative therapy
Authors
- Brian Badgwell
- Prajnan Das
- Jaffer Ajani
- Content type: Review
- Open Access
- Published: 15 August 2017
- Article: 149
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Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles
Authors (first, second and last of 14)
- Yanara Marincevic-Zuniga
- Johan Dahlberg
- Ann-Christine Syvänen
- Content type: Research
- Open Access
- Published: 14 August 2017
- Article: 148
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Clinical trials of tyrosine kinase inhibitors for lung cancer in China: a review
Authors
- Shan Su
- Yi-Long Wu
- Content type: Review
- Open Access
- Published: 07 August 2017
- Article: 147
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PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy
Authors (first, second and last of 10)
- Junyu Long
- Jianzhen Lin
- Haitao Zhao
- Content type: Review
- Open Access
- Published: 03 August 2017
- Article: 146
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Syk inhibitors in clinical development for hematological malignancies
Authors
- Delong Liu
- Aleksandra Mamorska-Dyga
- Content type: Review
- Open Access
- Published: 28 July 2017
- Article: 145
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Drug-induced amino acid deprivation as strategy for cancer therapy
Authors
- Marcus Kwong Lam Fung
- Godfrey Chi-Fung Chan
- Content type: Review
- Open Access
- Published: 27 July 2017
- Article: 144
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Erratum to: Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2
Authors (first, second and last of 10)
- Ming-de Huang
- Wen-ming Chen
- Yong-qian Shu
- Content type: Erratum
- Open Access
- Published: 27 July 2017
- Article: 143
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Recent developments in immunotherapy of acute myeloid leukemia
Authors (first, second and last of 5)
- Felix S. Lichtenegger
- Christina Krupka
- Marion Subklewe
- Content type: Review
- Open Access
- Published: 25 July 2017
- Article: 142
This is part of 1 collection: -
Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40+ monocyte differentiation
Authors (first, second and last of 11)
- Jin Dai
- Pu Fang
- Hong Wang
- Content type: Review
- Open Access
- Published: 24 July 2017
- Article: 141
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miR-380-5p-mediated repression of TEP1 and TSPYL5 interferes with telomerase activity and favours the emergence of an “ALT-like” phenotype in diffuse malignant peritoneal mesothelioma cells
Authors (first, second and last of 6)
- Graziella Cimino-Reale
- Paolo Gandellini
- Marco Folini
- Content type: Research
- Open Access
- Published: 17 July 2017
- Article: 140
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The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model
Authors (first, second and last of 12)
- Yueh-Chwen Hsu
- Yu-Chiao Chiu
- Hwei-Fang Tien
- Content type: Research
- Open Access
- Published: 11 July 2017
- Article: 139
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Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
Authors (first, second and last of 11)
- Jianbiao Zhou
- Chonglei Bi
- Wee-Joo Chng
- Content type: Research
- Open Access
- Published: 11 July 2017
- Article: 138
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Randomized, double-blind, placebo-controlled phase III study of ixazomib plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma: China Continuation study
Authors (first, second and last of 21)
- Jian Hou
- Jie Jin
- Philippe Moreau
- Content type: Research
- Open Access
- Published: 06 July 2017
- Article: 137
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Ongoing clinical trials of PD-1 and PD-L1 inhibitors for lung cancer in China
Authors
- Si-Yang Liu
- Yi-Long Wu
- Content type: Review
- Open Access
- Published: 05 July 2017
- Article: 136
This is part of 1 collection: -
Superior GVHD-free, relapse-free survival for G-BM to G-PBSC grafts is associated with higher MDSCs content in allografting for patients with acute leukemia
Authors (first, second and last of 13)
- Qian Fan
- Hui Liu
- Qifa Liu
- Content type: Research
- Open Access
- Published: 04 July 2017
- Article: 135
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Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis
Authors (first, second and last of 15)
- Ying-Jun Chang
- Yu Wang
- Xiao-Jun Huang
- Content type: Research
- Open Access
- Published: 04 July 2017
- Article: 134
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MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer
Authors (first, second and last of 5)
- Veronica Tisato
- Rebecca Voltan
- Giorgio Zauli
- Content type: Review
- Open Access
- Published: 03 July 2017
- Article: 133
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The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis
Authors (first, second and last of 11)
- Yujia Xu
- Zubin Zhang
- Xinliang Mao
- Content type: Research
- Open Access
- Published: 03 July 2017
- Article: 132
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Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q)
Authors (first, second and last of 18)
- Pierre Fenaux
- Aristoteles Giagounidis
- Alan F. List
- Content type: Research
- Open Access
- Published: 26 June 2017
- Article: 131
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Comparison of matched sibling donors versus unrelated donors in allogeneic stem cell transplantation for primary refractory acute myeloid leukemia: a study on behalf of the Acute Leukemia Working Party of the EBMT
Authors (first, second and last of 24)
- Eolia Brissot
- Myriam Labopin
- Arnon Nagler
- Content type: Research
- Open Access
- Published: 24 June 2017
- Article: 130
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A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients
Authors (first, second and last of 16)
- Marzia Vezzalini
- Andrea Mafficini
- Claudio Sorio
- Content type: Research
- Open Access
- Published: 21 June 2017
- Article: 129
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Single- or double-unit UCBT following RIC in adults with AL: a report from Eurocord, the ALWP and the CTIWP of the EBMT
Authors (first, second and last of 13)
- Frédéric Baron
- Annalisa Ruggeri
- Arnon Nagler
- Content type: Research
- Open Access
- Published: 21 June 2017
- Article: 128
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Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair
Authors (first, second and last of 19)
- Ana-Alicia López-Iglesias
- Ana B. Herrero
- Enrique M. Ocio
- Content type: Research
- Open Access
- Published: 20 June 2017
- Article: 127
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Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes
Authors (first, second and last of 6)
- Michela Sica
- Tommaso Rondelli
- Rosario Notaro
- Content type: Research
- Open Access
- Published: 19 June 2017
- Article: 126