The prediction of plasma and brain levels of 2,3,5,6-tetramethylpyrazine following transdermal application Xiaohong QiChrisita AckermannHuimin Hou OriginalPaper 10 July 2015 Article: 46
A thermogravimetric analysis of non-polymeric pharmaceutical plasticizers: Kinetic analysis, method validation, and thermal stability evaluation Aditya S. TatavartiDavid DollimoreKenneth S. Alexander OriginalPaper 10 July 2015 Article: 45
Chitosan and sodium alginate—Based bioadhesive vaginal tablets Amal El-KamelMagda SokarSafaa Al Gamal OriginalPaper 10 July 2015 Article: 44
Pharmacodynamic modeling of chemotherapeutic effects: Application of a transit compartment model to characterize methotrexate effects in vitro Evelyn D. LoboJoseph P. Balthasar OriginalPaper 10 July 2015 Article: 42
Deposition of nanoparticles in the arterial vessel by porous balloon catheters: Localization by confocal laser scanning microscopy and transmission electron microscopy Ulrich WestedtLucian Barbu-TudoranThomas Kissel OriginalPaper 10 July 2015 Article: 41
An in vitro examination of the impact of polyethylene glycol 400, pluronic P85, and vitamin E d-a-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine Brendan M. JohnsonWilliam N. CharmanChristopher J. H. Porter OriginalPaper 10 July 2015 Article: 40
Introduction: A welcome to the first special animal health issue of AAPS PharmSci Marilyn MartinezStefan Soback OriginalPaper 10 July 2015 Article: 39
Pharmacokinetic/pharmacodynamic integration in drug development and dosage-regimen optimization for veterinary medicine Pierre-Louis Toutain OriginalPaper 10 July 2015 Article: 38
Impact of antimicrobial resistance on regulatory policies in veterinary medicine: Status report Linda TollefsonWilliam T. Flynn OriginalPaper 10 July 2015 Article: 37
The role of the clinical pharmacologist in animal health Cory LangstonCyril R. Clarke OriginalPaper 10 July 2015 Article: 36
Dissolution test development for complex veterinary dosage forms: Oral boluses Raafat FahmyBill MarnaneR. Gary Hollenbeck OriginalPaper 10 July 2015 Article: 35
Interspecies considerations in the evaluation of human food safety for veterinary drugs Arthur L. CraigmillKristy A. Cortright OriginalPaper 10 July 2015 Article: 34
Evolving importance of biologics and novel delivery systems in the face of microbial resistance Terry L. Bowersock OriginalPaper 10 July 2015 Article: 33
Linking human and veterinary health: Trends, directions and initiatives Marilyn MartinezMichael J Rathbone OriginalPaper 10 July 2015 Article: 32
Quantitative comparison of functional screening by measuring intracellular Ca2+ with radioligand binding at recombinant human dopamine receptors Matthias U. Kassack OriginalPaper 10 July 2015 Article: 31
Role of plasma lipoproteins in modifying the toxic effects of water-insoluble drugs: Studies with cyclosporine A Kishor M. WasanManisha RamaswamyKathy D. Boulanger OriginalPaper 10 July 2015 Article: 30
Detection of MDR1 single nucleotide polymorphisms C3435T and G2677T using real-time polymerase chain reaction: MDR1 single nucleotide polymorphism genotyping assay Pengfei SongShen LiCharles R. Yates OriginalPaper 10 July 2015 Article: 29
Effects of obesity on the pharmacodynamics of nitroglycerin in conscious rats Ellen Q. WangHo-Leung Fung OriginalPaper 10 July 2015 Article: 28
Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis Ulrika WählbyE. Niclas JonssonMats O. Karlsson OriginalPaper 10 July 2015 Article: 27
Peptide delivery to the brain via adsorptive-mediated endocytosis: Advances with SynB vectors Guillaume DrinChristophe RousselleJamal Temsamani OriginalPaper 10 July 2015 Article: 26
Pharmacokinetics, mass balance, and tissue distribution of a novel DNA alkylating agent, VNP40101M, in rats John MaoYang XuBijan Almassain OriginalPaper 10 July 2015 Article: 24
Bioinformatic analysis of the human μ opioid receptor (OPRM1) splice and polymorphic variants Lili XinZaijie Jim Wang OriginalPaper 10 July 2015 Article: 23
Population analysis of the pharmacokinetics and pharmacodynamics of RWJ-270201 (BCX-1812) in treating experimental influenza A and B virus in healthy volunteers Ganesh R. IyerSam LiaoJoseph Massarella OriginalPaper 10 July 2015 Article: 22
Monitoring intracellular pH changes in response to osmotic stress and membrane transport activity using 5-chloromethylfluorescein Aline SalviJ. Mark QuillanWolfgang Sadée OriginalPaper 10 July 2015 Article: 21
Bioerodible injectable poly(ortho ester) for tetracycline controlled delivery to periodontal pockets: Preliminary trial in humans K. Schwach-AbdellaouiP. J. LoupR. Gurny OriginalPaper 10 July 2015 Article: 20
Which concentration of the inhibitor should be used to predict in vivo drug interactions from in vitro data? Kiyomi ItoKoji ChibaYuichi Sugiyama OriginalPaper 10 July 2015 Article: 20
Preformulation development of recombinant pegylated staphylokinase SY161 using statistical design Frank Bedu-AddoRandall MoreadithSiddharth J. Advant OriginalPaper 10 July 2015 Article: 19
