The million-molecule challenge: a moonshot project to rapidly advance longevity intervention discovery Mitchell B. LeeBenjamin BlueMatt Kaeberlein ORIGINAL ARTICLE 11 July 2023 Pages: 3103 - 3113
Systemic inflammatory and gut microbiota responses to fracture in young and middle-aged mice Joseph L. RobertsBrandon ChiedoHicham Drissi Original Article 12 October 2023 Pages: 3115 - 3129
Targeted metabolomics reveals plasma biomarkers and metabolic alterations of the aging process in healthy young and older adults Paniz JasbiJanko Nikolich-ŽugichHaiwei Gu ORIGINAL ARTICLE 17 May 2023 Pages: 3131 - 3146
A metabolomic signature of decelerated physiological aging in human plasma Georges E. JanssensLotte GrevendonkRiekelt H. Houtkooper ORIGINAL ARTICLE Open access 31 May 2023 Pages: 3147 - 3164
Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study Michelle H. ZonneveldStella TrompetRaymond Noordam ORIGINAL ARTICLE Open access 13 May 2023 Pages: 3165 - 3174
Associations between PBMC whole genome transcriptome, muscle strength, muscle mass, and physical performance in healthy home-dwelling older women Ana R. S. de SousaInger OttestadJacob J. Christensen ORIGINAL ARTICLE Open access 19 May 2023 Pages: 3175 - 3186
Pan-primate studies of age and sex Steve HorvathAmin HaghaniPeter W. Nathanielsz ORIGINAL ARTICLE Open access 26 July 2023 Pages: 3187 - 3209
The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms Zoltan UngvariVince Fazekas-PongorSetor K. Kunutsor Review Open access 26 July 2023 Pages: 3211 - 3239
Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases Ramasamy SelvaraniHoang Van Michelle NguyenArlan Richardson ORIGINAL ARTICLE Open access 04 October 2023 Pages: 3241 - 3256
Systemic inflammation and biological aging in the Health and Retirement Study Helen C. S. MeierColter MitchellJessica D. Faul ORIGINAL ARTICLE Open access 27 July 2023 Pages: 3257 - 3265
Cellular senescence and frailty: a comprehensive insight into the causal links Serena MarcozziGiorgia BigossiMarco Malavolta REVIEW 04 October 2023 Pages: 3267 - 3305
Vascular senescence and leak are features of the early breakdown of the blood–brain barrier in Alzheimer’s disease models Ka Ka TingPaul ColemanJennifer R. Gamble ORIGINAL ARTICLE Open access 02 October 2023 Pages: 3307 - 3331
Assessment of cerebral autoregulatory function and inter-hemispheric blood flow in older adults with internal carotid artery stenosis using transcranial Doppler sonography-based measurement of transient hyperemic response after carotid artery compression Rita Magyar-StangHanga PálRóbert Debreczeni Original Article Open access 21 August 2023 Pages: 3333 - 3357
Comparative analysis of the molecular and physiological consequences of constitutive SKN-1 activation Carmen M. RamosSean P. Curran ORIGINAL ARTICLE Open access 26 September 2023 Pages: 3359 - 3370
Resilience, aging, and response to radiation exposure (RARRE) in nonhuman primates: a resource review George W. SchaafJamie N. JusticeJ. Mark Cline REVIEW 16 May 2023 Pages: 3371 - 3379
Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures Tamas PandicsDavid MajorZoltan Ungvari REVIEW Open access 09 September 2023 Pages: 3381 - 3408
Association between aging-related biomarkers and longitudinal trajectories of intrinsic capacity in older adults Wan-Hsuan LuSophie GuyonnetPhilipe de Souto Barreto Original Article 24 August 2023 Pages: 3409 - 3418
Impact of influenza, herpes zoster, and pneumococcal vaccinations on the incidence of cardiovascular events in subjects aged over 65 years: a systematic review Alexandra AddarioThomas CĂ©larierElisabeth Botelho-Nevers REVIEW 03 June 2023 Pages: 3419 - 3447
Investigating the associations between upper limb motor function and cognitive impairment: a scoping review Kaylee D. RuddKatherine LawlerJane Alty REVIEW Open access 20 June 2023 Pages: 3449 - 3473
Calorie restriction mimetic drugs could favorably influence gut microbiota leading to lifespan extension Tomoya ShintaniHideya ShintaniHisashi Ashida REVIEW Open access 30 June 2023 Pages: 3475 - 3490
Deprescribing in cardiometabolic conditions in older patients: a systematic review Elizabeth HickmanMansha SeawoodharrySamuel Seidu REVIEW Open access 05 July 2023 Pages: 3491 - 3512
Prefrontal hemodynamic features of older adults with preserved visuospatial working memory function Tsz-lok LeeZihan DingAgnes S. Chan ORIGINAL ARTICLE Open access 27 July 2023 Pages: 3513 - 3527
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT) Gavin PharaohVarun KamatDavid J. Marcinek ORIGINAL ARTICLE Open access 18 July 2023 Pages: 3529 - 3548
Basal autophagic flux measured in blood correlates positively with age in adults at increased risk of type 2 diabetes Julien BensalemXiao Tong TeongTimothy J. Sargeant ORIGINAL ARTICLE 27 July 2023 Pages: 3549 - 3560