1. The Open-Artery Hypothesis: Introduction

   • Carey D. Kimmelstiel

   OriginalPaper Pages: 165 - 165

2. Acute Coronary Syndromes: Molecular Basis for Cardiac Risk Factors

   • Richard H. Karas

   OriginalPaper Pages: 167 - 175

3. Pathobiology of Myocardial Necrosis

   • Bruce F. Waller

   OriginalPaper Pages: 177 - 184

4. Pathobiology and Clinical Impact of Reperfusion Injury

   • Yochai Birnbaum
   • Jonathan Leor
   • Robert A. Kloner

   OriginalPaper Pages: 185 - 195

5. Adjunctive Pharmacologic Treatment: Focus on the Development of Low Molecular Weight Heparins

   • Richard C. Becker
   • Fred Spencer

   OriginalPaper Pages: 197 - 205

6. Assessment of Regional Viability in the Infarct Zone Following Myocardial Infarction

   • James E. Udelson
   • David Criss

   OriginalPaper Pages: 207 - 216

7. Invasive Strategies to Achieve Infarct-Related Artery Patency

   • John J. Smith

   OriginalPaper Pages: 217 - 225

8. The Open-Artery Hypothesis: An Overview

   • Carey D. Kimmelstiel
   • Deeb N. Salem

   OriginalPaper Pages: 227 - 237

9. Coronary Artery Patency and Survival in Clinical Trials

   • Christopher J. Ellis
   • John K. French
   • Harvey D. White

   OriginalPaper Pages: 239 - 250

10. The Open Artery: Electrophysiologic Considerations

    • Connor J. Haugh
    • Munther K. Homoud
    • N. A. Mark Estes III

    OriginalPaper Pages: 251 - 258

11. Early, Complete Infarct Vessel Patency: Arriving at a Gold Standard for Future Clinical Investigation in Myocardial Reperfusion

    • Todd L. Johnson
    • Eric J. Topol

    OriginalPaper Pages: 259 - 266

12. Key References in the Open-Artery Hypothesis

    • Carey D. Kimmelstiel

    OriginalPaper Pages: 267 - 270

13. The Essence Trial: Efficacy and Safety of Subcutaneous Enoxaparin in Unstable Angina and Non-Q-Wave MI: A Double-Blind, Randomized, Parallel-Group, Multicenter Study Comparing Enoxaparin and Intravenous Unfractionated Heparin: Methods and Design

    • Marc Cohen
    • Reginald Blaber
    • Alexander G.G. Turpie

    OriginalPaper Pages: 271 - 274

14. Prospective Comparison of Patient Characteristics and Outcome of Non-prior Aspirin Users versus Aspirin Users with Unstable Angina or Non-Q-Wave Myocardial Infarction Treated with Combination Antithrombotic Therapy

    • Marc Cohen
    • Philip C. Adams
    • Valentin Fuster

    OriginalPaper Pages: 275 - 280

15. Rescue PTCA Following Failed Thrombolysis and Primary PTCA: A Retrospective Study of Angiographic and Clinical Outcome

    • Frits W. Bär
    • Tom Jm Oude Ophnis
    • Hein J. Wellens

    OriginalPaper Pages: 281 - 288

16. Low-Dose Vitamin K Therapy in Excessively Anticoagulated Patients: A Dose-Finding Study

    • Mary Therese Brophy
    • Louis David Fiore
    • Daniel Deykin

    OriginalPaper Pages: 289 - 292

17. Adjunctive Therapy with an Antithrombotic Drug Can Prevent Reocclusion and Induce Residual Thrombus Reduction After Percutaneous Transcatheter Angioplasty of the Thrombotic Lesions

    • Hiroaki Kawano
    • Takanobu Tomaru
    • Yasumi Uchida

    OriginalPaper Pages: 293 - 300