1. Dedication and editorial preface

   • Dr. Janson

   OriginalPaper Pages: iii - iii

2. The many faces of PNA

   • Peter E. Nielsen

   OriginalPaper Pages: 135 - 147

3. Modulation of nucleic acid information processing by PNAs: potential use in anti-viral therapeutics

   • Lionel Bastide
   • Bernard Lebleu
   • Ian Robbins

   OriginalPaper Pages: 149 - 159

4. Targeted gene delivery: the role of peptide nucleic acid

   • Kenneth W. Liang
   • Feng Liu
   • Leaf Huang

   OriginalPaper Pages: 161 - 167

5. Imaging gene expression in the brain with peptide nucleic acid (PNA) antisense radiopharmaceuticals and drug targeting technology

   • Ruben J. Boado
   • William M. Pardridge

   OriginalPaper Pages: 169 - 190

6. Receptor-specific targeting with complementary peptide nucleic acids conjugated to peptide analogs and radionuclides

   • Eric Wickstrom
   • Mathew L. Thakur
   • Edward R. Sauter

   OriginalPaper Pages: 191 - 214

7. Morpholinos and PNAs compared

   • James E. Summerton

   OriginalPaper Pages: 215 - 236

8. Chemistry of locked nucleic acids (LNA): Design, synthesis, and bio-physical properties

   • Jesper Wengel
   • Michael Petersen
   • Troels Koch

   OriginalPaper Pages: 237 - 253

9. Recent applications of RNA interference (RNAi) in mammalian systems

   • Lisa Scherer
   • John J. Rossi

   OriginalPaper Pages: 255 - 267

10. Peptide nucleic acids as epigenetic inhibitors of HIV-1

    • Shizuko Sei

    OriginalPaper Pages: 269 - 286

11. Therapeutic uses of peptide nucleic acids (PNA) in oncology

    • Nadia Zaffaroni
    • Raffaella Villa
    • Marco Folini

    OriginalPaper Pages: 287 - 296

12. PNAs as novel cancer therapeutics

    • Luca Mologni
    • Carlo Gambacorti-Passerini

    OriginalPaper Pages: 297 - 308

13. Medicinal chemistry of plasmid DNA with peptide nucleic acids: A new strategy for gene therapy

    • Olivier Zelphati
    • Jiin Felgner
    • Philip Felgner

    OriginalPaper Pages: 309 - 323

14. Locked nucleic acids (LNA) and medical applications

    • Henrik Ørum
    • Andreas Wolter
    • Lars Kongsbak

    OriginalPaper Pages: 325 - 334

15. Peptide nucleic acids as agents to modify target gene expression and function

    • Gan Wang
    • Peter M. Glazer

    OriginalPaper Pages: 335 - 345

16. Peptide nucleic acids: Cellular delivery and recognition of DNA and RNA targets

    • David R. Corey

    OriginalPaper Pages: 347 - 352

17. The use of PNAs and their derivatives in mitochondrial gene therapy

    • P. M. Smith
    • G. F. Ross
    • R. N. Lightowlers

    OriginalPaper Pages: 353 - 360

18. Gene silencing through RNA interference: Potential for therapeutics and functional genomics

    • David O. Azorsa
    • Spyro Mousses
    • Natasha J. Caplen

    OriginalPaper Pages: 361 - 372

19. Transcriptional activation of human CREB gene promoter using bis-PNA (peptide nucleic acid)

    • Christopher G. Janson
    • Matthew During
    • Paola Leone

    OriginalPaper Pages: 373 - 376