Multiple-Pool Cell Lifespan Model of Hematologic Effects of Anticancer Agents Wojciech KrzyzanskiWilliam J. Jusko OriginalPaper Pages: 311 - 337
Clinical Trial Simulation Using Therapeutic Effect Modeling: Application to Ivabradine Efficacy in Patients with Angina Pectoris Sylvie ChabaudPascal GirardJean-Pierre Boissel OriginalPaper Pages: 339 - 363
Gastric Acid Secretion in the Dog: A Mechanism-Based Pharmacodynamic Model for Histamine Stimulation and Irreversible Inhibition by Omeprazole Angela ÄbelöBjörn HolsteinMats O. Karlsson OriginalPaper Pages: 365 - 382
Modeling Nicotine Arterial–Venous Differences to Predict Arterial Concentrations and Input Based on Venous Measurements: Application to Smokeless Tobacco and Nicotine Gum Maria PitsiuJean-Michel GriesDavide Verotta OriginalPaper Pages: 383 - 402
Commentary on Significance Levels for Covariate Effects in NONMEM Stuart L. Beal Commentary Pages: 403 - 410
Announcement: Pharmacokinetic–Pharmacodynamic Modeling: Concepts and Applications, May 18–21, 2003, Buffalo, New York Announcement Pages: 413 - 413