1. At the doorstep into the third year

   • K. Wüthrich

   Editorial Pages: 259 - 259

2. NMR structure-based drug design

   • Stephen W. Fesik

   Perspective Pages: 261 - 269

3. The three-dimensional structure of acyl-coenzyme A binding protein from bovine liver: Structural refinement using heteronuclear multidimensional NMR spectroscopy

   • Kim Vilbour Andersen
   • Flemming M. Poulsen

   Research Papers Pages: 271 - 284

4. Heteronuclear three-dimensional NMR spectroscopy of a partially denatured protein: The A-state of human ubiquitin

   • Brian J. Stockman
   • Annica Euvrard
   • Terrence A. Scahill

   Research Papers Pages: 285 - 296

5. Measurement of two- and three-bond ¹³C−¹H J couplings to the C_δ carbons of leucine residues in staphylococcal nuclease

   • Geerten W. Vuister
   • Toshimasa Yamazaki
   • Ad Bax

   Research Papers Pages: 297 - 306

6. Extensive distance geometry calculations with different NOE calibrations: New criteria for structure selection applied to Sandostatin and BPTI

   • Hans Widmer
   • Armin Widmer
   • Werner Braun

   Research Papers Pages: 307 - 324

7. [2-³H]ATP synthesis and ³H NMR spectroscopy of enzyme-nucleotide complexes: ADP and ADP.V_i bound to myosin subfragment 1

   • Stefan Highsmith
   • Mark Kubinec
   • David E. Wemmer

   Research Papers Pages: 325 - 334

8. Measurement of proton relaxation rates in proteins

   • Benoit Boulat
   • Geoffrey Bodenhausen

   Research Papers Pages: 335 - 348

9. A 4D HCC(CO)NNH experiment for the correlation of aliphatic side-chain and backbone resonances in ¹³C/¹⁵N-labelled proteins

   • Robin T. Clowes
   • Wayne Boucher
   • Ernest D. Laue

   Short Communications Pages: 349 - 354

10. SESAME: A least-squares approach to the evaluation of protein structures computed from NMR data

    • Ju-xing Yang
    • T. F. Havel

    Short Communications Pages: 355 - 360

11. A computationally efficient method for evaluating the gradient of 2D NOESY intensities

    • Ping F. Yip

    Short Communications Pages: 361 - 365

12. Pseudo-3D NMR spectroscopy: Application to oligo- and polysaccharides

    • Dušan Uhrín
    • Jean-Robert Brisson
    • David R. Bundle

    Short Communications Pages: 367 - 373