1. Model based on GRID-derived descriptors for estimating CYP3A4 enzyme stability of potential drug candidates

   • Patrizia Crivori
   • Ismael Zamora
   • Italo Poggesi

   OriginalPaper Pages: 155 - 166

2. VEGA – An open platform to develop chemo-bio-informatics applications, using plug-in architecture and script programming

   • Alessandro Pedretti
   • Luigi Villa
   • Giulio Vistoli

   OriginalPaper Pages: 167 - 173

3. Ligand intramolecular motions in ligand-protein interaction: ALPHA, a novel dynamic descriptor and a QSAR study with extended steroid benchmark dataset

   • Kari Tuppurainen
   • Marja Viisas
   • Reino Laatikainen

   OriginalPaper Pages: 175 - 187

4. Validation of an empirical RNA-ligand scoring function for fast flexible docking using RiboDock®

   • S. David Morley
   • Mohammad Afshar

   OriginalPaper Pages: 189 - 208

5. A promising enantioselective Diels–Alder dienophile by computer-assisted rational design: 2,5-diphenyl-1-vinyl-borolane

   • Silvina C. Pellegrinet
   • María A. Silva
   • Jonathan M. Goodman

   OriginalPaper Pages: 209 - 214

6. A correlation study of quinoline derivatives and their pharmaceutical behavior by ab initio calculated NQR parameters

   • Marjan A. Rafiee
   • Nasser L. Hadipour
   • Hossein Naderi-manesh

   OriginalPaper Pages: 215 - 220

7. Instructions for authors

   Instructions for Authors Pages: 221 - 224